Axial spondyloarthritis (axSpA) was historically considered a disease of men, largely due to
the recognition of a more severe, progressive phenotype, ankylosing spondylitis (AS; or …

Introduction Axial involvement in spondyloarthritis has significantly evolved from the original
1984 New York criteria for ankylosing spondylitis, leading to an improved understanding of …

Objective Polymorphisms in the antifungal signalling molecule CARD9 are associated with
ankylosing spondylitis (AS). Here, we investigated the cellular mechanism by which CARD9 …

Introduction Psoriatic arthritis (PsA) is a complex and heterogeneous inflammatory disease.
Secukinumab, a biologic disease-modifying antirheumatic drug (bDMARD), has extensive …

Objectives This study aims to evaluate in a real-life Italian multicenter cohort of axial
spondyloarthritis (axSpA)(1) the 4-year effectiveness and safety of secukinumab,(2) the drug …

The therapeutic response of patients with psoriatic arthritis (PsA) varies greatly and is often
unsatisfactory. Accordingly, it is essential to individualise treatment selection to minimise …

Abstract Introduction Psoriasis (PsO) is an immune-mediated chronic inflammatory disease
that results in severe outcomes that impact the patient's quality of life and work productivity …

Psoriasis is a chronic, immune-mediated, inflammatory skin disease, associated with
multiple comorbidities and psychological and psychiatric disorders. The quality of life of …