Background: To recognize the action of pharmacologically approved anticancer drugs in
biological systems, information regarding its pharmacokinetics, such as its transport within …

Albumin, a dominant protein in human plasma, possesses remarkable physiological
attributes that render it an exceptional candidate for cancer treatment. On the one hand …

The intermolecular interaction of fosinopril, an angiotensin converting enzyme inhibitor with
bovine serum albumin (BSA), has been investigated in physiological buffer (pH 7.4) by multi …

The ability to bind plasma proteins helps in comprehending relevant aspects related to the
pharmacological properties of many drugs. Despite the vital role of the drug mubritinib …

In the present study, the interaction of the novel synthesized platinum complex named
methyl-glycine 1, 10-phenanthroline platinum nitrate product with two most crucial blood …

Breast cancer is among the deadliest cancers worldwide, highlighting the urgent need for
effective treatments. This study employs density functional theory (DFT) and molecular …

Ibrutinib (IBR) is a novel Bruton's tyrosine kinase inhibitor and shows good efficacy for
several B-cell malignancies. In the current study, the molecular mechanism of the interaction …

Human serum albumin (HSA) nanoparticles are considered to be versatile carrier of
anticancer agents in efficiently delivering the drug to the tumor site without causing any …

The competition among drugs for binding to plasma proteins is regarded as a
pharmacokinetic drug interaction. Competition between antitumor agents and other drugs for …

Small molecule 5BMF is a novel mitochondria-targeted delocalized lipophilic cation (DLC)
with good anti-tumor activity and fluorescence emission suitable for bioimaging. In this study …