Effective evaluation and prediction of aerosol transport deposition in the human respiratory
tracts are critical to aerosol drug delivery and evaluation of inhalation products …

The dynamics of respiratory airflows and the associated transport mechanisms of inhaled
aerosols characteristic of the deep regions of the lungs are of broad interest in assessing …

Over the past years, advanced in vitro pulmonary platforms have witnessed exciting
developments that are pushing beyond traditional preclinical cell culture methods. Here, we …

Pulmonary drug delivery represents an attractive, non-invasive administration option. In
addition to locally acting drugs, molecules that are intended to produce systemic effects can …

Background and objective From various perspectives (eg inhalation exposure and drug
delivery), it is important to provide insights into the behavior of inhaled particles in the …

Elongated drug particles have the potential to be superior to spherical drug particles for
delivery to the deep lung due to their increased ability to align with the airflow. However, the …

The past decade has witnessed tremendous endeavors to deliver novel preclinical in vitro
lung models for pulmonary research endpoints, including foremost with the advent of organ …

Recognizing the significance of drug carriers in the treatment of atherosclerotic plaque is
crucial in light of the worldwide repercussions of ischemic stroke. Conservative …

Inhaled medications are widely accepted as being the optimal route for treating pediatric
respiratory diseases, a leading cause of hospitalization and death. Despite jet nebulizers …

Despite the prevalence of inhalation therapy in the treatment of various respiratory diseases,
predicting and optimizing lung deposition fractions of inhaled drugs for maximal efficacy …