The influence of human immunodeficiency virus-1 on hematopoiesis

A Moses, J Nelson, GC Bagby Jr - Blood, The Journal of the …, 1998 - ashpublications.org
THROMBOCYTOPENIA, anemia, lymphocytopenia, mono-cytopenia, and neutropenia and
permutations of these abnormalities are found in most patients with acquired …

Pathogenesis and pathophysiology of anemia in HIV infection

KA Kreuzer, JK Rockstroh - Annals of hematology, 1997 - Springer
Anemia occurs frequently among patients seropositive for human immunodeficiency virus
(HIV), but its multifactorial origin complicates its differential diagnosis and adequate …

Human immunodeficiency virus infection of bone marrow endothelium reduces induction of stromal hematopoietic growth factors [see comments]

AV Moses, S Williams, ML Heneveld, J Strussenberg… - 1996 - ashpublications.org
The majority of human immunodeficiency virus (HIV)-seropositive patients develop bone
marrow abnormalities associated with hematopoietic malfunction during the progression of …

Neutropenia in human immunodeficiency virus infection: data from the women's interagency HIV study

AM Levine, R Karim, W Mack, DJ Gravink… - Archives of internal …, 2006 - jamanetwork.com
Background: Neutropenia is well described in individuals infected with human
immunodeficiency virus (HIV) and occurs in approximately 10% to 50% of cases. Neither the …

tat protein stimulates production of transforming growth factor-beta 1 by marrow macrophages: a potential mechanism for human immunodeficiency virus-1-induced …

G Zauli, BR Davis, MC Re, G Visani, G Furlini… - 1992 - ashpublications.org
In this study, we examined the potential role of the human immunodeficiency virus (HIV) tat
protein in causing the hematopoietic abnormalities frequently observed in HIV-infected …

Single-stranded RNA derived from HIV-1 serves as a potent activator of NK cells

G Alter, TJ Suscovich, N Teigen, A Meier… - The Journal of …, 2007 - journals.aai.org
Persistent immune activation is a hallmark of chronic viremic HIV-1 infection. Activation of
cells of the innate immune system, such as NK cells, occurs rapidly upon infection, and is …

Expression of the Human Immunodeficiency Virus Type-1 Coreceptors CXCR-4 (fusin, LESTR) and CKR-5 in CD34+ Hematopoietic Progenitor Cells

M Deichmann, R Kronenwett… - Blood, The Journal of the …, 1997 - ashpublications.org
CD34+ hematopoietic progenitor cells were assessed for mRNA expression of the human
immunodeficiency virus type-1 (HIV-1) coreceptors CXCR-4, also termed fusin or LESTR …

Pathogenesis of anemia during human immunodeficiency virus infection

RD Semba, GE Gray - Journal of Investigative Medicine, 2001 - journals.sagepub.com
Anemia is common during human immunodeficiency virus (HIV) infection1 and is associated
with increased progression to AIDS2 and higher mortality. 3 It is estimated that up to 90% of …

Infection of human marrow stroma by human immunodeficiency virus-1 (HIV-1) is both required and sufficient for HIV-1–induced hematopoietic suppression in vitro …

I Bahner, K Kearns, S Coutinho… - Blood, The Journal …, 1997 - ashpublications.org
Patients with human immunodeficiency virus-1 (HIV-1) infection often present with bone
marrow (BM) failure that may affect all hematopoietic lineages. It is presently unclear …

T cell dynamics in HIV-1 infection

DR Clark, RJ de Boer, KC Wolthers, F Miedema - Advances in immunology, 1999 - Elsevier
Publisher Summary This chapter discusses the T cell dynamics in HIV-1 infection. One of the
most prominent features of HIV-1 infection is CD4+ T cell depletion. This statement is widely …