Examining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts

J Laaksonen, PP Mishra, I Seppälä, LP Lyytikäinen… - Scientific Reports, 2021 - nature.com
High blood pressure (BP) is a major risk factor for many noncommunicable diseases. The
effect of mitochondrial DNA single-nucleotide polymorphisms (mtSNPs) on BP is less known …

A benchmarking of human mitochondrial DNA haplogroup classifiers from whole-genome and whole-exome sequence data

V García-Olivares, A Muñoz-Barrera… - Scientific reports, 2021 - nature.com
The mitochondrial genome (mtDNA) is of interest for a range of fields including evolutionary,
forensic, and medical genetics. Human mitogenomes can be classified into evolutionary …

Profiling of mitochondrial DNA heteroplasmy in a prospective oral squamous cell carcinoma study

L Fendt, F Fazzini, H Weissensteiner, E Bruckmoser… - Cancers, 2020 - mdpi.com
While a shift in energy metabolism is essential to cancers, the knowledge about the
involvement of the mitochondrial genome in tumorigenesis and progression in oral …