Once it became clear that inflammation takes place in the modulation of different
degenerative disease including neurodegenerative, cardiovascular, diabetes and cancer …

Cell adhesion molecules (CAMs) are transmembrane proteins that mediate adhesion and
interactions between cells or cell and extra-cellular matrix. Increased expression and …

The NLR family, pyrin domain‐containing 3 (NLRP3) inflammasome is a reactive oxygen
species‐sensitive multiprotein complex that regulates IL‐1β maturation via caspase‐1. It …

Although concern remains about the athero-thrombotic risk posed by cyclo-oxygenase
(COX)-2-selective inhibitors, recent data implicates rofecoxib, while celecoxib appears …

Emerging evidence supports an intertwining framework for the involvement of different
inflammatory pathways in a common pathological background for a number of disorders. Of …

Selenium as a component of glutathione peroxidase may be beneficial in insulin resistance,
hence potentially may modify the risk of diabetes and cardiovascular disease. The aim of our …

Endothelial dysfunctions that include decreased nitric oxide (NO) bioactivity and increased
endothelin-1 (ET-1) bioactivity have been considered to be involved in the pathogenesis of …

Nimesulide, a COX-2 preferential inhibitor with a favorable gastric and cardiovascular safety
profile, was responsible for some cases of acute liver failure attributed to the nitrobenzene …

Increased levels of free fatty acid (FFA)-induced endothelial dysfunction play an important
role in the initiation and development of atherosclerosis. Feprazone is a nonsteroidal anti …

Prostaglandins (PGs) and their specific receptors play critical roles in atherothrombosis.
Produced from arachidonic acid via two cyclooxygenase (COX) isoforms, PGs mediate their …