Background There is emerging evidence that the development and progression of
osteoarthritis (OA) is associated with inflammation. C reactive protein (CRP), a systemic …

The aims of this study were to conduct a systematic literature review on balneotherapy about
the specific therapeutic role of mineral elements and other chemical compounds of mineral …

Mesenchymal stem cells (MSCs) have been demonstrated to serve as targets for the
treatment of osteoarthritis (OA) and exosomes derived from MSCs also display …

Humic substances are effective in the suppression of delayed type hypersensitivity, rat paw
oedema, a graft‐versus‐host reaction and contact hypersensitivity in rats. They reduce the C …

Balneotherapy (BT) is one of the most commonly used non-pharmacologic complementary
therapies for different rheumatic diseases. Its beneficial properties probably derived from a …

Frailty is not limited to the elderly, as patients with rheumatic diseases can also experience
this condition. The present scoping review aimed to investigate the possibility of using the …

Knee osteoarthritis (OA) is a degenerative disease which is expected to become one of the
leading causes of disability by the next years. This work aims to assess if balneotherapy and …

A review was undertaken of the investigations carried out on peloids and pelotherapy
considering only the publications in English. More than 300 publications including articles …

Background Osteoarthritis (OA) is a public health problem that will probably increase in the
future with the aging of the population. Crenobalneotherapy is commonly used to treat OA …

The objective of this prospective parallel randomized single-blind study was to assess that a
cycle of mud-bath therapy (MBT) provides any benefits over usual treatment in patients with …