The combination of heterocycles offers a new opportunity to create novel multicyclic
compounds having improved biological activity. Coumarins are ubiquitous natural …

This article emphasizes on the importance of benzofuran as a biologically relevant
heterocycle. It covers most of the physiologically as well as medicinally important …

In nature's collection of biologically active heterocycles, benzofuran derivatives constitute a
major group. The broad spectrum of pharmacological activity in individual benzofurans …

4-Phenyl-5-pyridin-4-yl-4H-1, 2, 4-triazole-3-thiol (3) was obtained in basic media via the
formation of 2-isonicotinoyl-N-phenylhydrazinecarbothioamide (2), and converted to some …

The furan nucleus is found in a large number of biologically active materials. In recent years,
many natural furan derivatives were isolated and their biological effects were investigated. In …

Research on natural products containing benzofuran has remarkably increased during the
past few decades. Newly isolated natural products with complex structures are being …

Resistance to antibiotics is a major global problem and there is an urgent need to develop
new therapeutic agents. Although many classes of active compounds have been …

The reaction of salicylaldehyde with 1-chloro-3-mesitylacetone (2) and potassium carbonate
was used to prepare 1-(1-benzofuran-2-yl)-2-mesitylethanone (4) for the starting reagent …

Abstract a series of 2-oxospiro [indoline-3, 4′-pyran] derivatives 4 and 7 were obtained in
good yield under mild conditions from the one-pot reaction of indole-2, 3-dione derivatives 1 …

Introduction: Benzofuran moiety constitutes the core of several interesting pharmacologically
active natural products. Benzofurans are among feasible potent active inhibitors against …