Epigenetic regulation of asthma and allergic disease

P Bégin, KC Nadeau - Allergy, Asthma & Clinical Immunology, 2014 - Springer
Epigenetics of asthma and allergic disease is a field that has expanded greatly in the last
decade. Previously thought only in terms of cell differentiation, it is now evident the …

Current perspective on eicosanoids in asthma and allergic diseases: EAACI Task Force consensus report, part I

M Sokolowska, GE Rovati, Z Diamant, E Untersmayr… - Allergy, 2021 - Wiley Online Library
Eicosanoids are biologically active lipid mediators, comprising prostaglandins, leukotrienes,
thromboxanes, and lipoxins, involved in several pathophysiological processes relevant to …

Farm exposure and time trends in early childhood may influence DNA methylation in genes related to asthma and allergy

S Michel, F Busato, J Genuneit, J Pekkanen… - Allergy, 2013 - Wiley Online Library
Background Genetic susceptibility and environmental influences are important contributors
to the development of asthma and atopic diseases. Epigenetic mechanisms may facilitate …

Epigenetics, asthma, and allergic diseases: a review of the latest advancements

S Lovinsky-Desir, RL Miller - Current allergy and asthma reports, 2012 - Springer
Environmental epigenetic regulation in asthma and allergic disease is an exciting area that
has gained a great deal of scientific momentum in recent years. Environmental exposures …

A review of epigenetic changes in asthma: methylation and acetylation

M Sheikhpour, M Maleki, M Ebrahimi Vargoorani… - Clinical …, 2021 - Springer
Several studies show that childhood and adulthood asthma and its symptoms can be
modulated through epigenetic modifications. Epigenetic changes are inheritable …

Genome-wide DNA methylation assay reveals novel candidate biomarker genes in cervical cancer

SA Farkas, N Milutin-Gašperov, M Grce, TK Nilsson - Epigenetics, 2013 - Taylor & Francis
The oncogenic human papilloma viruses (HPVs) are associated with precancerous cervical
lesions and development of cervical cancer. The DNA methylation signatures of the host …

Genetic polymorphisms and associated susceptibility to asthma

ME March, PMA Sleiman… - International journal of …, 2013 - Taylor & Francis
As complex common diseases, asthma and allergic diseases are caused by the interaction
of multiple genetic variants with a variety of environmental factors. Candidate-gene studies …

Epigenetics in asthma and COPD

M Kabesch, IM Adcock - Biochimie, 2012 - Elsevier
Epigenetic mechanisms are likely to play a role in many complex diseases, the extent of
which we only beginning to understand. COPD and asthma are two respiratory diseases …

Early life precursors, epigenetics, and the development of food allergy

X Hong, X Wang - Seminars in immunopathology, 2012 - Springer
Food allergy (FA), a major clinical and public health concern worldwide, is caused by a
complex interplay of environmental exposures, genetic variants, gene–environment …

Role of epigenetics and the transcription factor Sp1 in the expression of the D prostanoid receptor 1 in human cartilage

M Najar, SG Alsabri, GG Guedi, M Merimi… - Frontiers in Cell and …, 2023 - frontiersin.org
D prostanoid receptor 1 (DP1), a prostaglandin D2 receptor, plays a central role in the
modulation of inflammation and cartilage metabolism. We have previously shown that …