Necrotic, apoptotic and autophagic cell fates triggered by nanoparticles

R Mohammadinejad, MA Moosavi, S Tavakol… - Autophagy, 2019 - Taylor & Francis
Nanomaterials have gained a rapid increase in use in a variety of applications that pertain to
many aspects of human life. The majority of these innovations are centered on medical …

The toxicological mechanisms of environmental soot (black carbon) and carbon black: focus on oxidative stress and inflammatory pathways

R Niranjan, AK Thakur - Frontiers in immunology, 2017 - frontiersin.org
The environmental soot and carbon blacks (CBs) cause many diseases in humans, but their
underlying mechanisms of toxicity are still poorly understood. Both are formed after the …

In vitro cytotoxicity effect and antibacterial performance of human lung epithelial cells A549 activity of zinc oxide doped TiO2 nanocrystals: investigation of bio-medical …

K Kaviyarasu, N Geetha, K Kanimozhi… - Materials Science and …, 2017 - Elsevier
We report the synthesis of high quality ZnO doped TiO 2 nanocrystals by chemical method at
room temperature (RT), it can cause serious oxidative stress and DNA damage to human …

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

ST Stern, PP Adiseshaiah, RM Crist - Particle and fibre toxicology, 2012 - Springer
The study of the potential risks associated with the manufacture, use, and disposal of
nanoscale materials, and their mechanisms of toxicity, is important for the continued …

Toxicity assessment of nanomaterials: methods and challenges

A Dhawan, V Sharma - Analytical and bioanalytical chemistry, 2010 - Springer
The increasing use of nanomaterials in consumer and industrial products has aroused
global concern regarding their fate in biological systems, resulting in a demand for parallel …

Assessing nanoparticle toxicity

SA Love, MA Maurer-Jones… - Annual review of …, 2012 - annualreviews.org
Nanoparticle toxicology, an emergent field, works toward establishing the hazard of
nanoparticles, and therefore their potential risk, in light of the increased use and likelihood of …

Causes of genome instability: the effect of low dose chemical exposures in modern society

SAS Langie, G Koppen, D Desaulniers… - …, 2015 - academic.oup.com
Genome instability is a prerequisite for the development of cancer. It occurs when genome
maintenance systems fail to safeguard the genome's integrity, whether as a consequence of …

Assessment of respiratory and reproductive impacts of artisanal refinery activities on male Albino Wistar rats: Implications for environmental health

PG Suku, E Ugwoha, OF Orikpete… - Bulletin of the National …, 2023 - Springer
Background Artisanal petroleum refining operations have been known to produce a
significant volume of air pollutants. The highest concentration of pollutants is generated …

Cytotoxicity and oxidative stress induced by different metallic nanoparticles on human kidney cells

I Pujalté, I Passagne, B Brouillaud, M Tréguer… - Particle and fibre …, 2011 - Springer
Background Some manufactured nanoparticles are metal-based and have a wide variety of
applications in electronic, engineering and medicine. Until now, many studies have …

Resolution of inflammation: mechanisms and opportunity for drug development

AL Alessandri, LP Sousa, CD Lucas, AG Rossi… - Pharmacology & …, 2013 - Elsevier
Inflammation is a beneficial host reaction to tissue damage and has the essential primary
purpose of restoring tissue homeostasis. Inflammation plays a major role in containing and …