Background Alzheimer's disease (AD) is the most common neurodegenerative disease
worldwide, and an updated quantification of its impact on morbidity, disability, and mortality …

The concept of frailty, now being adopted in most medical disciplines, is attracting growing
interest in neurology. Every day, most neurologists care for patients with varying degrees of …

Background Management of geriatric patients would be simplified if a universally accepted
definition of frailty for clinical use was defined. Among definitions of frailty, Fried frailty …

Abstract Background The CAnadian REgistry for Pulmonary Fibrosis (CARE-PF) is a multi-
center, prospective registry designed to study the natural history of fibrotic interstitial lung …

Background: Both physical frailty and cognitive impairment predict death, but the joint effect
of these two factors is uncertain. The objectives are to determine if the Mini-mental state …

Background It is unknown whether the association between delirium and mortality is
consistent for individuals across the whole range of health states. A bimodal relationship has …

Objective To develop survival prediction tables to inform physicians and patients about
survival probabilities after the diagnosis of dementia and to determine whether survival after …

Background The debate on frailty in later life focuses primarily on deficits and their
associations with adverse (health) outcomes. In addition to deficits, it may also be important …

Anorexia of aging is a complex geriatric syndrome and a direct risk factor for frailty and thus
should not be accepted as normal consequence of aging. Early diagnosis and formulating a …

Background According to some studies, interventions can prevent or delay frailty, but their
effect in preventing adverse outcomes in frail community-dwelling older people is unclear …