Zebrafish patient avatars in cancer biology and precision cancer therapy

M Fazio, J Ablain, Y Chuan, DM Langenau… - Nature Reviews …, 2020 - nature.com
In precision oncology, two major strategies are being pursued for predicting clinically
relevant tumour behaviours, such as treatment response and emergence of drug resistance …

Toxicological study of metal and metal oxide nanoparticles in zebrafish

C Bai, M Tang - Journal of applied toxicology, 2020 - Wiley Online Library
Metal and metal oxide nanoparticles have been widely used in catalytic, electronic and
biomedical fields. It is necessary to investigate their toxicity and potential hazards to human …

Polystyrene microplastics induce apoptosis via ROS-mediated p53 signaling pathway in zebrafish

S Umamaheswari, S Priyadarshinee… - Chemico-biological …, 2021 - Elsevier
Microplastic (MP) pollution is ubiquitous and has become an emerging threat to aquatic
biota. Recent scientific reports have recorded their toxic impacts at the cellular and organism …

Ecotoxicological assessment of Ti 3 C 2 T x (MXene) using a zebrafish embryo model

GK Nasrallah, M Al-Asmakh, K Rasool… - Environmental Science …, 2018 - pubs.rsc.org
The recent application of 2D Ti3C2Tx (MXene) nanomaterials as adsorbents and
membranes for water treatment as well as for biomedical applications is attracting a growing …

Using zebrafish for investigating the molecular mechanisms of drug‐induced cardiotoxicity

ZZ Zakaria, FM Benslimane… - BioMed research …, 2018 - Wiley Online Library
Over the last decade, the zebrafish (Danio rerio) has emerged as a model organism for
cardiovascular research. Zebrafish have several advantages over mammalian models. For …

[HTML][HTML] Engineering spatial-organized cardiac organoids for developmental toxicity testing

P Hoang, A Kowalczewski, S Sun, TS Winston… - Stem Cell Reports, 2021 - cell.com
Emerging technologies in stem cell engineering have produced sophisticated organoid
platforms by controlling stem cell fate via biomaterial instructive cues. By micropatterning …

Toxic effects of polystyrene nanoplastics and polybrominated diphenyl ethers to zebrafish (Danio rerio)

Q Wang, Y Li, Y Chen, L Tian, D Gao, H Liao… - Fish & Shellfish …, 2022 - Elsevier
Nanoplastics (NPs) are good carriers of persistent organic pollutants (POPs) such as
polybrominated diphenyl ethers (PBDEs), and can alter their bioavailability and toxic …

Cardiovascular toxicity and anxiety-like behavior induced by deltamethrin in zebrafish (Danio rerio) larvae

M Li, XY Liu, XZ Feng - Chemosphere, 2019 - Elsevier
Deltamethrin is widely used because of its low toxicity and high efficiency. Although its
potential toxicity has been reported, its effects on cardiovascular system and motor behavior …

The cardiovascular toxicity induced by high doses of gatifloxacin and ciprofloxacin in zebrafish

R Shen, Y Yu, R Lan, R Yu, Z Yuan, Z Xia - Environmental Pollution, 2019 - Elsevier
As a new type of pollutant, fluoroquinolones (FQs) antibiotics are ubiquitous in environment
and have some threat to human health and ecological environment. Their ecological toxicity …

AHR-mediated oxidative stress contributes to the cardiac developmental toxicity of trichloroethylene in zebrafish embryos

H Jin, C Ji, F Ren, S Aniagu, J Tong, Y Jiang… - Journal of hazardous …, 2020 - Elsevier
Trichloroethylene (TCE), a widely used chlorinated solvent, is a common environmental
pollutant. Current evidence shows that TCE could induce heart defects during embryonic …