Celiac disease and endocrine autoimmunity–the genetic link

GJ Kahaly, L Frommer, D Schuppan - Autoimmunity reviews, 2018 - Elsevier
Celiac disease is a small intestinal inflammatory disease with autoimmune features that is
triggered and maintained by the ingestion of the storage proteins (gluten) of wheat, barley …

Zonulin as a potential putative biomarker of risk for shared type 1 diabetes and celiac disease autoimmunity

LK Wood Heickman, MD DeBoer… - … research and reviews, 2020 - Wiley Online Library
The incidence of type 1 diabetes (T1D) is increasing annually, in addition to other childhood‐
onset autoimmune diseases. This review is inspired by recent strides in research defining …

Prevalence of celiac disease in 52,721 youth with type 1 diabetes: international comparison across three continents

ME Craig, N Prinz, CT Boyle, FM Campbell… - Diabetes …, 2017 - Am Diabetes Assoc
OBJECTIVE Celiac disease (CD) has a recognized association with type 1 diabetes. We
examined international differences in CD prevalence and clinical characteristics of youth …

[HTML][HTML] Association between type 1 diabetes mellitus and celiac disease: Autoimmune disorders with a shared genetic background

GVF Monar, H Islam, SM Puttagunta, R Islam, S Kundu… - Cureus, 2022 - ncbi.nlm.nih.gov
Type 1 diabetes mellitus (T1DM) and celiac disease (CD) are one of the most recognized
related autoimmune disorders as they share a common genetic background that has been …

Co-occurrence of type 1 diabetes and celiac disease autoimmunity

W Hagopian, HS Lee, E Liu, M Rewers, JX She… - …, 2017 - publications.aap.org
METHODS: In this prospective birth cohort study, 8676 children at high genetic risk of both
diseases were enrolled and 5891 analyzed in median follow-up of 66 months. Along with …

HLA-DQA1 and HLA-DQB1 alleles, conferring susceptibility to celiac disease and type 1 diabetes, are more expressed than non-predisposing alleles and are …

F Farina, S Picascia, L Pisapia, P Barba, S Vitale… - Cells, 2019 - mdpi.com
HLA DQA1* 05 and DQB1* 02 alleles encoding the DQ2. 5 molecule and HLA DQA1* 03
and DQB1* 03 alleles encoding DQ8 molecules are strongly associated with celiac disease …

Phenome-wide Mendelian randomization analysis reveals multiple health comorbidities of coeliac disease

S Yuan, F Jiang, J Chen, B Lebwohl, PHR Green… - …, 2024 - thelancet.com
Summary Background Coeliac disease (CeD) has been associated with a broad range of
diseases in observational data; however, whether these associations are causal remains …

Common ground: shared risk factors for type 1 diabetes and celiac disease

EF Verdu, JS Danska - Nature immunology, 2018 - nature.com
Risk factors for most autoimmune diseases are multifactorial genetic variants modified by
environmental risk factors. Type 1 diabetes and celiac disease share high-risk HLA …

Genotypes predisposing for celiac disease and autoimmune diabetes and risk of infections in early childhood

K Størdal, G Tapia, NA Lund‐Blix… - Journal of pediatric …, 2024 - Wiley Online Library
Objectives Infections in early childhood have been associated with risk of celiac disease
(CD) and type 1 diabetes (T1D). We investigated whether this is driven by susceptibility …

Transglutaminase antibodies and celiac disease in children with type 1 diabetes and in their family members

A Parkkola, T Härkönen, SJ Ryhänen, R Uibo… - Pediatric …, 2018 - Wiley Online Library
Objectives We set out to determine the prevalence of tissue transglutaminase antibodies
(anti‐tTG) and celiac disease (CD) in children with newly diagnosed type 1 diabetes (T1D) …