Many first-line treatments for neglected tropical diseases identified by the World Health
Organization (WHO) are limited by one or more of the following: the development of drug …

Research efforts on the medicinal chemistry of vanadium have been mainly focused whether
on improving biodistribution and tolerability of the vanadium insulin-enhancing core or on …

Abstract Chagas disease and Human African trypanosomiasis (HAT) are caused by
Trypanosoma cruzi, T. brucei rhodesiense or T. b. gambiense parasites, respectively; while …

Among the infectious illnesses designated by the World Health Organization (WHO) as
neglected tropical diseases (NTDs), four illnesses are major health concerns in the …

In the search for new metal-based drugs for the treatment of tumoral and parasitic diseases
a vanadyl complex,[VIVO (SO4)(H2O) 2 (dppz)]· 2H2O, that includes the bidentate …

In the search for new therapeutic tools against Chagas' disease (American
Trypanosomiasis) four novel mixed-ligand vanadyl complexes,[VIVO (L2-2H)(L1)], including …

To date treatment of trypanosomiasis urgently requires new effective and non-toxic drugs.
The article covers some of the achievements in the search for new antitrypanosomal agents; …

In the search for new metal-based drugs for the treatment of Chagas disease, the most
widespread Latin American parasitic disease, novel complexes of the bioactive ligand …

Upon the screening of 16 antiproliferative compounds against Toxoplasma gondii and
Neospora caninum, two hydrolytically stable ruthenium complexes (compounds 16 and 18) …

In this review, we intend to provide a general view of the evolution of experimental studies in
the area of chemotherapy for Chagas disease. We can follow the process of drug …