The Earth turns on its axis every 24 h; almost all life on the planet has a mechanism—
circadian rhythmicity—to anticipate the daily changes caused by this rotation. The molecular …

Inflammation not only plays a crucial role in acute ischemic cardiac injury, but also
contributes to post-infarction repair and remodeling. Traditionally, neutrophils have been …

Background On-pump cardiac surgery provokes a predictable perioperative myocardial
ischaemia–reperfusion injury which is associated with poor clinical outcomes. We …

In the past decade, it has become increasingly evident that the circadian clock system plays
an important role in many physiological processes. The circadian clock can be divided into 2 …

It has been well established that the circadian clock plays a crucial role in the regulation of
almost every physiological process. It also plays a critical role in pathophysiological states …

Myocardial infarction (MI) is the leading cause of death in Western countries.
Epidemiological studies show acute MI to be more prevalent in the morning and to be …

Time plays a crucial role in the regulation of physiological processes. Without a temporal
control system, animals would be unprepared for cyclic environmental changes, negatively …

Objectives: The goal of this study was to test the unverified assumption that chronically
elevated cardiac troponin T (cTnT) levels fluctuate randomly around a homeostatic set point …

Abstract Study Objectives: Older adults and patients with dementia often have disrupted
circadian activity rhythms (CARs). Disrupted CARs are associated with health declines and …

Circadian rhythms exert a profound impact on most aspects of mammalian physiology,
including the immune and cardiovascular systems. Leukocytes engage in time-of-day …