Background In 2021, an estimated 4800 people developed rifampicin-resistant tuberculosis
in Mozambique, 75% of which went undiagnosed. Detailed molecular data on rifampicin …

Abstract The World Health Organization has a goal of universal drug susceptibility testing for
patients with tuberculosis. However, molecular diagnostics to date have focused largely on …

Background The treatment of multidrug‐resistant (MDR‐) and extensively drug‐resistant
tuberculosis (XDR‐TB) is a formidable challenge. Treatment of MDR‐and XDR‐TB using …

Background Emerging resistance to bedaquiline (BDQ) threatens to undermine advances in
the treatment of drug-resistant tuberculosis (DRTB). Characterizing serial Mycobacterium …

Clofazimine (CFZ) and bedaquiline (BDQ) are currently used for the treatment of multidrug-
resistant (MDR) Mycobacterium tuberculosis (Mtb) strains. In recent years, adding CFZ and …

Kazakhstan ranks among the countries with the highest number of MDR-TB patients per
100,000 population worldwide. The successful transmission of local MDR strains of …

Despite their therapeutic benefits, antibiotics exert collateral damage on the microbiome and
promote antimicrobial resistance. However, the mechanisms governing microbiome …

This report documents the case of a Ukrainian patient infected with an extensively drug-
resistant (XDR) lineage 2 Mycobacterium tuberculosis strain harbouring the rifampicin …

Carbon dioxide (CO2) absorption is one of the key technologies in combating climate
change. With increasing concerns about the effects of greenhouse gases, carbon capture …

Background We sought to identify resistance patterns and key drivers of recent multidrug-
resistant tuberculosis (MDR-TB) transmission in a TB-prevalent area in Peru. Methods Cross …