The fornix is a white matter bundle located in the mesial aspect of the cerebral hemispheres,
which connects various nodes of a limbic circuitry and is believed to play a key role in …

Growing evidence highlights the importance of white matter in the pathogenesis of focal
epilepsy. Ex vivo and post-mortem studies show pathological changes in epileptic patients …

Since traumatic axonal injury (TAI) is implicated as a prominent pathology of concussion, we
examined potential sex differences in axon structure and responses to TAI. Rat and human …

While diffusion tensor imaging (DTI) has been extensively used to infer micro-structural
characteristics of cerebral white matter in human conditions, correlations between human in …

White matter microvascular alterations in temporal lobe epilepsy (TLE) may be relevant to
acquired neurodegenerative processes and cognitive impairments associated with this …

Using magnetic resonance imaging, it is possible to measure the behavior of diffusing water
molecules, and the metrics derived can be used as indirect markers of tissue micro …

Myelin is a vital element of normal brain development and structure. Myelination is most
prominent during the first two years of life and proceeds until the age of 30. Abnormal …

Alzheimer's disease (AD) is one of the most common progressive neurodegenerative
diseases associated with the degradation of memory and cognitive ability. Current …

Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy. The most frequent
pathologic finding in this condition is hippocampal sclerosis (HS). In addition, in a small …

Demyelination stands out as a prominent feature in individuals with specific types of
epilepsy. Concurrently, individuals with demyelinating diseases, such as multiple sclerosis …