Most diagnostic tests for tuberculosis (TB) rely on sputum samples, which are difficult to
obtain and have low sensitivity in immunocompromised patients, patients with disseminated …

The review discusses current knowledge of the biosynthesis, composition and arrangement
of the mycobacterial envelope, describes the biological activities of the constituents and …

This review describes the application of matrix‐assisted laser desorption/ionization (MALDI)
mass spectrometry to carbohydrate analysis and covers the period 1991–1998. The …

Approximately one third of the world's population is infected with Mycobacterium
tuberculosis, the causative agent of tuberculosis. This bacterium has an unusual lipid-rich …

Detailed structural and functional studies over the last decade have led to current
recognition of the mycobacterial lipoarabinomannan (LAM) as a phosphatidylinositol …

Robert Koch identified Mycobacterium tuberculosis as the causative agent of tuberculosis
(TB) in 1882 and was the first to realize that the efficacy of his early tuberculin therapies …

Lipoarabinomannans (LAM) and lipomannans (LM) are integral parts of the mycobacterial
cell wall recognized by cells involved in the innate immune response and have been found …

The control of Mycobacterium tuberculosis infection depends on recognition of the pathogen
and the activation of both the innate and adaptive immune responses. Toll-like receptors …

Mycobacterium tuberculosis, the causative agent of tuberculosis, is one of the most effective
human pathogens and the molecular basis of its virulence remains poorly understood. Here …

Abstract The Bcg/Nramp1 gene controls early resistance and susceptibility of macrophages
to mycobacterial infections. We previously reported that Mycobacterium tuberculosis …