Tomato is the highest value fruit and vegetable crop worldwide, yet produces α-tomatine, a
renowned toxic and bitter-tasting anti-nutritional steroidal glycoalkaloid (SGA) involved in …

Nonheme iron-dependent enzymatic reactions play crucial roles in building and modifying
bioactive organic molecules in all major classes of natural product pathways. While the …

Steroidal glycoalkaloids (SGAs) are specialized metabolites found in members of Solanum
species, and are also known as toxic substances in Solanum food crops such as tomato …

Plants synthesize tens of thousands of bioactive nitrogen-containing compounds called
alkaloids, including some clinically important drugs in modern medicine. The discovery of …

In photosynthetic tissues in the light, the function of energy production is associated primarily
with chloroplasts, while mitochondrial metabolism adjusts to balance ATP supply, regulate …

Steroidal glycoalkaloids (SGAs) constitute a characteristic class of antinutritional metabolites
that are found in certain Solanum species. Despite the considerable studies on SGA …

Unlike most plants, members of the genus Solanum produce cholesterol and use this as a
precursor for steroidal glycoalkaloids. The production of the compounds begins as a branch …

Abstract The 2-Oxoglutatrate-dependent dioxygenases (2OGDs) comprise the 2-
Oxoglutatrate and Fe (II)-dependent dioxygenases (2ODD) enzyme families that facilitate the …

Steroidal glycoalkaloids (SGAs) are specialized metabolites in Solanaceae that serve as
defensive compounds and undergo significant compositional changes during fruit ripening …

Steroids are an important family of bioactive compounds. Steroid drugs are renowned for
their multifaceted pharmacological activities and are the second-largest category in the …