Breakthroughs in molecular medicine have positioned the amyloid-β (Aβ) pathway at the
center of Alzheimer's disease (AD) pathophysiology. While the detailed molecular …

Peptide-based materials that have diverse structures and functionalities are an important
type of biomaterials. In former times, peptide-based nanomaterials with excellent stability …

The aggregation of proteins into amyloid fibrils and their deposition into plaques and
intracellular inclusions is the hallmark of amyloid disease. The accumulation and deposition …

A wide range of proteins have been reported to condensate into a dense liquid phase,
forming a reversible droplet state. Failure in the control of the droplet state can lead to the …

Hierarchical self-assembly and crystallization with long-range ordered spatial arrangement
is ubiquitous in nature and plays an essential role in the regulation of structures and …

Amyloid fibrils have traditionally been considered only as pathological aggregates in human
neurodegenerative diseases, but it is increasingly becoming clear that the propensity to form …

Condensed states of proteins, including liquid-like membraneless organelles and solid-like
aggregates, contribute in fundamental ways to the organisation and function of the cell …

Peptides and proteins have been found to possess an inherent tendency to convert from
their native functional states into intractable amyloid aggregates. This phenomenon is …

Self-assembling systems play a significant role in physiological functions and have therefore
attracted tremendous attention due to their great potential for applications in energy …

There is an emerging quest for lightweight materials with excellent mechanical properties
and economic production, while still being sustainable and functionalizable. They could form …