Age-related macular degeneration

M Fleckenstein, TDL Keenan, RH Guymer… - Nature reviews Disease …, 2021 - nature.com
Age-related macular degeneration (AMD) is the leading cause of legal blindness in the
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …

Therapeutic approaches for age-related macular degeneration

RM Galindo-Camacho, C Blanco-Llamero… - International journal of …, 2022 - mdpi.com
Damage to the retinal pigment epithelium, Bruch's membrane and/or tissues underlying
macula is known to increase the risk of age-related macular degeneration (AMD). AMD is …

Sirolimus loaded chitosan functionalized poly (lactic-co-glycolic acid)(PLGA) nanoparticles for potential treatment of age-related macular degeneration

R Suri, YR Neupane, N Mehra, M Nematullah… - International journal of …, 2021 - Elsevier
The usefulness of sirolimus (SIR) in the treatment of diseases that involve retinal
degeneration like age-related macular degeneration (AMD) has been well documented …

Cell-derived nanovesicles from mesenchymal stem cells as extracellular vesicle-mimetics in wound healing

YR Neupane, HK Handral, SA Alkaff, WH Chng… - … Pharmaceutica Sinica B, 2023 - Elsevier
Wound healing is a dynamic process that involves a series of molecular and cellular events
aimed at replacing devitalized and missing cellular components and/or tissue layers …

Human-induced pluripotent stem cells-derived retinal pigmented epithelium, a new horizon for cells-based therapies for age-related macular degeneration

S Dehghan, R Mirshahi, A Shoae-Hassani… - Stem Cell Research & …, 2022 - Springer
Retinal pigment epithelium (RPE) degeneration is the hallmark of age-related macular
degeneration (AMD). AMD, as one of the most common causes of irreversible visual …

Superparamagnetic Amine-Functionalized Maghemite Nanoparticles as a Thixotropy Promoter for Hydrogels and Magnetic Field-Driven Diffusion-Controlled Drug …

S Ganguly, P Das, S Srinivasan… - ACS Applied Nano …, 2024 - ACS Publications
Superparamagnetic nanoparticle-arrested hydrogel matrices have immense significance in
smart soft biomaterials. Herein, we report the synthesis of superparamagnetic nanoparticle …

[HTML][HTML] Age-Related Macular Degeneration (AMD): Pathophysiology, Drug Targeting Approaches, and Recent Developments in Nanotherapeutics

M Singh, R Negi, Alka, R Vinayagam, SG Kang… - Medicina, 2024 - mdpi.com
The most prevalent reason for vision impairment in aging inhabitants is age-related macular
degeneration (AMD), a posterior ocular disease with a poor understanding of the anatomic …

Nanodiagnostics and Nanotherapeutics for age-related macular degeneration

A Sarkar, S Dyawanapelly - Journal of Controlled Release, 2021 - Elsevier
Age-related macular degeneration (AMD) is the third leading cause worldwide blindness
that causes permanent central vision impairment in older people. Over the past few years …

Recent advances in targeted nanotherapeutic approaches for breast cancer management

P Gupta, YR Neupane, S Parvez, K Kohli - Nanomedicine, 2021 - Taylor & Francis
Breast cancer is the most commonly occurring tumor disease worldwide. Breast cancer is
currently managed by conventional chemotherapy, which is inadequate in curbing this …

[HTML][HTML] Compounding engineered mesenchymal stem cell-derived exosomes: A potential rescue strategy for retinal degeneration

Y Wang, X Liu, B Wang, H Sun, Y Ren… - Biomedicine & …, 2024 - Elsevier
The prevalence of retinal degenerative diseases, including age-related macular
degeneration and retinitis pigmentosa, has been increasing globally and is linked to the …