The prevalent view of developmental phenotypic switching holds that phenotype
modifications occurring during critical windows of development are “irreversible”–that is …

Natural populations of ectothermic oviparous vertebrates typically experience thermal
variability in their incubation environment. Yet an overwhelming number of laboratory …

In compliance to animal welfare 3Rs principle there is a great demand for refined tests
alternative to classical mammal teratogenicity tests. We propose a refined alternative …

To study contributions of N-methyl-D-aspartate receptors (NMDARs) in presynaptic and
postsynaptic neurons of the developing visual system, we microinject antisense Morpholino …

Xenopus tadpoles are a unique model for regeneration in that they exhibit two distinct
phases of age-specific regenerative competence. In Xenopus laevis, young tadpoles fully …

Many animals, especially those that develop externally, are equipped with innate color
preferences that promote survival. For example, Xenopus tadpoles are known to phototax …

Abstract The Xenopus Eleutheroembryonic Thyroid Assay (XETA) was recently published as
an OECD Test Guideline for detecting chemicals acting on the thyroid axis. However, the …

Nutrient status affects brain development; however, the effects of nutrient availability on
neural progenitor cell proliferation in vivo are poorly understood. Without food, Xenopus …

Developing animals absorb nutrients either through the placenta or from ingested food;
however, the mechanisms by which embryos use external nutrients for individual organ …

Xenopus laevis tadpoles exhibit an avoidance behavior when they encounter a moving
visual stimulus. A visual avoidance event occurs when a moving object approaches the eye …