Ice crystal growth in the freezing desalination process of binary water-NaCl system

H Yuan, K Sun, K Wang, J Zhang, Z Zhang, L Zhang… - Desalination, 2020 - Elsevier
In this study, ice crystal growth in the freezing desalination process of binary water-NaCl
system is investigated. The phase field method is used to conduct simulation and predict …

A phase-field model without artificial curvature effect for the crystal growth simulation

Y Li, Q Yu, S Ham, S Kwak, C Lee, J Kim - International Journal of Heat and …, 2023 - Elsevier
In this study, we present a novel phase-field model without artificial curvature effect for the
crystal growth simulation. Most phase-field models for dendritic growth are based on the …

Phase-field modeling of wetting and balling dynamics in powder bed fusion process

L Li, JQ Li, TH Fan - Physics of Fluids, 2021 - pubs.aip.org
In a powder bed fusion additive manufacturing process, the balling effect has a significant
impact on the surface quality of the printing parts. Surface wetting helps the bonding …

Dendritic morphology and growth inhibition of ice crystals in sucrose solutions

JQ Li, M Rahman, S Patel, RH Bogner… - Crystal Growth & …, 2022 - ACS Publications
The impact of freeze-concentrated solutes on ice crystal growth is not well understood in
pharmaceutical processes. We present a quantitative analysis of the inhibition of anisotropic …

Raman spectroscopy as a process analytical technology to investigate biopharmaceutical freeze concentration processes

D Weber, J Hubbuch - Biotechnology and Bioengineering, 2021 - Wiley Online Library
Freezing processes are a well‐established unit operation in the biopharmaceutical industry
to increase the shelf‐life of protein‐based drugs. While freezing reduces degradation …

Real-time observation of the freezing stage of the mannitol solution using high-resolution optical microscopy

L Chun, M Sha, Z Naijun, L Zhiqiang… - International Journal of …, 2023 - Elsevier
Vacuum freeze-drying has been expanding its influence in many fields, and the freezing
stage is of utmost importance for the freeze-drying process. However, the limited …

Structural correlation between a crystal and the substrate: A dynamic density functional prediction

Y Liu, H Zeng - Chemical Engineering Science, 2024 - Elsevier
In material preparing, the freezing on a structured substrate is an important process that
determines the molecular structure of the product but the mechanism is still not very clear at …

[HTML][HTML] Phase and thermal diffusivity variation of saline water diagnosed by visual and temperature method during freezing process

SC Huang, CC Cheng, HP Cheng - Results in Engineering, 2024 - Elsevier
Freezing step is a fundamental physical phenomenon of cooling a liquid formulation for
guaranteeing product quality. In this study, freezing process of saline water under various …

Phase-field modeling of selective laser brazing of diamond grits

L Li, S Li, B Zhang, TH Fan - Physics of Fluids, 2021 - pubs.aip.org
Diamond grit is widely used in cutting, grinding, and polishing tools for its superior
mechanical properties and performance in machining hard materials. Selective laser …

Stresses, Stabilization, and Recent Insights in Freezing of Biologics

R Fang, P Sane, I Borges Sebastião… - Principles and Practices of …, 2023 - Springer
Freeze-thawing is a critical unit operation during manufacturing of biopharmaceuticals. A
significant fraction of biologics drug substances are stored frozen. While the number of …