The promise and challenges of genomics‐informed periodontal disease diagnoses

L Nibali, K Divaris, EMC Lu - Periodontology 2000, 2024 - Wiley Online Library
Recent advances in human genomics and the advent of molecular medicine have
catapulted our ability to characterize human and health and disease. Scientists and …

Neutrophils and neutrophil extracellular traps in oral health and disease

TS Kim, NM Moutsopoulos - Experimental & Molecular Medicine, 2024 - nature.com
Neutrophils perform essential functions in antimicrobial defense and tissue maintenance at
mucosal barriers. However, a dysregulated neutrophil response and, in particular, the …

[HTML][HTML] RNAseq of Gingival Fibroblasts Exposed to PRF Membrane Lysates and PRF Serum

A Imani, L Panahipour, H Kühtreiber, M Mildner… - Cells, 2024 - mdpi.com
Platelet-rich fibrin (PRF) is prepared by spontaneous coagulation of fractionated blood.
When squeezed between two plates, PRF is separated into solid PRF membranes and a …

Fibrin aggravates periodontitis through inducing NETs formation from mitochondrial DNA

Y Chen, E Mei, S Nan, X Chen, P Zhang, Q Zhu… - Oral …, 2024 - Wiley Online Library
Objectives This study investigated the role of fibrin on neutrophil extracellular traps (NETs)
formation from neutrophils and to elucidate the involvement of mitochondria in NETs …

CC chemokine receptor 5 and CC chemokine ligand 5 gene polymorphisms in patients with periodontitis-A case–control study

AK Muralidharan, S Subramanian, PSG Prakash… - Gene Reports, 2024 - Elsevier
Aim This study aimed to evaluate the association of CC Chemokine Receptor 5 (CCR5)
G59029A and CC Chemokine Ligand 5 (CCL5)-28 C/G gene polymorphisms in patients with …

Unravelling the Impact of Blood Metabolites, and Lifestyle Factors on Periodontal Disease Using Mendelian Randomization

R Charles - 2024 - search.proquest.com
Periodontal disease remains a global public health concern. Despite the availability of
preventive and therapeutic strategies, the multifactorial nature of periodontitis complicates its …

Age-related Comparison of Protein Composition in Serum and Platelet-Rich Fibrin (PRF)

A Parmar - 2024 - search.proquest.com
Periodontal disease is one of several inflammatory disease that is found with a higher
prevalence in the older adult populations. The pro-inflammatory cytokines IL-6 and TNF- …

Type I Interferon Protects Against Bone Loss in Periodontitis by Mitigating an Interleukin (Il)-17-Neutrophil Axis

S Zhang, J Zhang, A Wang, M Lin, N Yu, K Moss… - Available at SSRN … - papers.ssrn.com
Abstract Type I interferons (IFNs-I), a group of pleiotropic cytokines, critically modulate host
response in various inflammatory diseases. However, the role of the IFN-I pathway in …