Malaria has been the pre-eminent cause of early mortality in many parts of the world
throughout much of the last five thousand years and, as a result, it is the strongest force for …

Malaria still has a devastating impact on public health and welfare in Cameroon. Despite the
increasing number of studies conducted on disease prevalence, transmission patterns or …

Parasites of the genus Plasmodium have a complex life cycle. They alternate between their
final mosquito host and their intermediate hosts. The parasite can be either extra-or …

Plasmodium vivax is the main cause of malarial disease in Asia and South America.
Plasmodium vivax infection was thought to be absent in African populations who are Duffy …

The overwhelming dominance of Duffy blood group negativity among most people living in
sub-Saharan Africa has been considered the basis of their protection from endemic …

A better understanding of the occurrence and risk of Plasmodium vivax infection among
Duffy-negative individuals is required to guide further research on these infections across …

The ability of the malaria parasite Plasmodium vivax to invade erythrocytes is dependent on
the expression of the Duffy blood group antigen on erythrocytes. Consequently, Africans …

ACKR1, located on chromosome 1q23. 2, is the gene that encodes a glycoprotein
expressing the Duffy blood group antigens. This gene is transcribed in two mRNA variants …

Plasmodium vivax was thought to infect only the erythrocytes of Duffy blood group positive
people. In the last decade, P. vivax has appeared throughout Africa, both in areas where …

Background Plasmodium vivax infection is known to be rare in West/Central Africa, the most
accepted explanation being the lack of expression of erythroid Duffy antigen in the local …