Exploration of structurally novel natural products greatly facilitates the discovery of
biologically active pharmacophores that are biologically validated starting points for the …

The direct difunctionalization of alkenes has emerged as a sustainable and versatile
strategy for the efficient construction of complex molecules from simple chemical feedstocks …

A one-step enantioselective and diastereodivergent α-allylation of unprotected α-hydroxy
indanones has been developed using an Ir/Zn dual catalyst system; no additional base is …

In this work, benzotriazolium salts have been introduced as efficient, readily accessible,
bench-stable Lewis acid catalysts. Though these sorts of N-heterocyclic compounds have …

Recent genomic studies have demonstrated that fungi can possess gene clusters encoding
for the production of previously unobserved secondary metabolites. Activation of these …

The ring-reorganizing transformations of activated cyclopropanes are typically achieved
under acidic conditions. This Letter describes the first acid-free and Lewis base-mediated …

An intriguing tandem Michael/lactonization reaction of α-hydroxy-1-indanones and
methyleneindolinones has been established in this work. The employment of chiral …

An endophytic fungus Paraphaeosphaeria neglecta FT462 isolated from the Hawaiian-plant
Lycopodiella cernua (L.) Pic. Serm produced one unusual compound (1 …

The enantioselective [3+ 2] annulation of α-hydroxy-1-indanones with yne–enones was
accomplished using dinuclear zinc catalysts via a Brønsted base and Lewis acid …

Five previously undescribed ambuic acid derivatives, pestallic acids A–E and three known
analogs were isolated from the cultured broth of Pestalotiopsis sp. FT172. The structures of …