Diabetes mellitus is one of the biggest challenges for the scientific community in the 21st
century. It is a well-recognized multifactorial health problem contributes significantly to high …

Oxadiazole is a five-membered heterocyclic compound containing two nitrogen atoms and
one oxygen atom. The 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole have favourable physical …

A new series of nortopsentin analogs, in which the central imidazole ring of the natural lead
was replaced by a 1, 3, 4-oxadiazole or 1, 3, 4-thiadiazole moiety, was efficiently …

Aims: Synthesis of 4-fluorobenzohydrazide Schiff bases and 1, 3, 4-oxadiazole analogs has
a DPPH radical scavenging potential. Background: Synthetic antioxidants are widely used …

Current antidiabetic medications have a plethora of harmful side effects, and most of the
drugs do not contain 1, 3, 4-oxadiazole moiety. Therefore, research into the development of …

The extracellular signal-regulated kinase 5 (Erk5) signaling plays a crucial role in cancer,
and regulating its activity may have potential in cancer chemotherapy. In this study, a series …

Diabetes mellitus (DM) is a multifaceted metabolic disorder that remains a major threat to
global health security. Sadly, the clinical relevance of available drugs is burdened with an …

This study aim to synthesize new 1, 3, 4-oxadiazole derivatives incorporating mefenamic
acid as promising α-glucosidase and urease inhibitors, potentially leading to the treatment of …

Abstract A novel series of 3, 3′-bisindolylmethanes was successfully synthesized from a
xylochemical 5-hydroxymethylfurfural, by condensing with indoles 3a-l employing a green …

Abstract A library of 3-(5-[(substituted benzyl) sulfanyl]-1, 3, 4-oxadiazol-2-yl)-N-substituted
pyridine-2-amines and 2-[(5-{2-[(substituted phenyl) amino] pyridin-3-yl}-2, 3-dihydro-1, 3, 4 …