asteRIa enables robust interaction modeling between chromatin modifications and epigenetic readers

M Stadler, S Lukauskas, T Bartke… - Nucleic Acids …, 2024 - academic.oup.com
Chromatin, the nucleoprotein complex consisting of DNA and histone proteins, plays a
crucial role in regulating gene expression by controlling access to DNA. Chromatin …

Unbiased learning of protein conformational representation via unsupervised random forest

M Sahil, N Ahalawat, J Mondal - bioRxiv, 2024 - biorxiv.org
Accurate data representation is paramount in biophysics to capture the functionally relevant
motions of biomolecules. Traditional feature selection methods, while effective, often rely on …

Uncover Methodological Strategies For Biomarker Discovery In Two Sepsis Cohorts

E Palm - 2024 - diva-portal.org
In recent decades, the number of measurable parameters in biological samples has
skyrocketed. The increase in the amount of measurement available to the number of …

Dimensionality reduction methods for high-dimensional biological data analysis

KT Capraz - 2024 - archiv.ub.uni-heidelberg.de
Disease progression and response to treatments can strongly differ between patients, due to
each individual's unique genetic, environmental and molecular factors. Precision medicine …