Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

Homocysteine (Hcy) is a sulfur-containing amino acid generated during methionine
metabolism, accumulation of which may be caused by genetic defects or the deficit of …

Cathepsin S (CTSS), a lysosomal protease, belongs to a family of cysteine cathepsin
proteases that promote degradation of damaged proteins in the endolysosomal pathway …

Small vessel disease (SVD) is one of the most frequent pathological conditions which lead
to dementia. Biochemical and neuroimaging might help correctly identify the clinical …

Cardiovascular disease (CVD) is responsible for the majority of deaths in the developed
world. Particularly, in patients with chronic kidney disease (CKD), the imbalance of calcium …

A series of chalcone derivatives bearing benzamide or benzenesulfonamide moieties were
synthesized and evaluated for their anti-tumor effect on HCT116, MCF7 and 143B cell lines …

Cathepsin S (CatS) is one of the cysteinyl cathepsins widely studied for its clinical
significance and found to be a promising therapeutic target for several diseases; to name a …

The cysteine protease cathepsin S (CatS) is overexpressed in many tumors. It is known to be
involved in tumor progression as well as antigen processing in antigen‐presenting cells …

Cardiovascular diseases (CVDs) have long been a serious threat to human health and
longevity. Cathepsins are involved in a variety of human physiological processes and have …

Cathepsin K and S are two isoforms of cysteine protease with diverse biological functions in
the aspect of osteoporosis and autoimmune diseases. Accordingly, the homologous …