Alpha-lipoic acid: An antioxidant with anti-aging properties for disease therapy

M Shanaida, R Lysiuk, O Mykhailenko… - Current Medicinal …, 2025 - benthamdirect.com
The anti-aging effects of alpha-lipoic acid (αLA), a natural antioxidant synthesized in human
tissues, have attracted a growing interest in recent years. αLA is a short-chain sulfur …

The role of dietary nutrients in peripheral nerve regeneration

M El Soury, BE Fornasari, G Carta, F Zen… - International journal of …, 2021 - mdpi.com
Peripheral nerves are highly susceptible to injuries induced from everyday activities such as
falling or work and sport accidents as well as more severe incidents such as car and …

[HTML][HTML] The impact of supplements on recovery after peripheral nerve injury: a review of the literature

Y Abushukur, R Knackstedt - Cureus, 2022 - ncbi.nlm.nih.gov
Peripheral nerve injury (PNI) can result from trauma, surgical resection, iatrogenic injury,
and/or local anesthetic toxicity. Damage to peripheral nerves may result in debilitating …

Amelioration of metal-induced cellular stress by α-lipoic acid and dihydrolipoic acid through antioxidative effects in PC12 cells and Caco-2 cells

KFB Hossain, M Akter, MM Rahman, MT Sikder… - International Journal of …, 2021 - mdpi.com
α-Lipoic acid (ALA) and its reduced form dihydrolipoic acid (DHLA) are endogenous dithiol
compounds with significant antioxidant properties, both of which have the potential to …

Effects of Theranekron and alpha-lipoic acid combined treatment on GAP-43 and Krox-20 gene expressions and inflammation markers in peripheral nerve injury

L Sencar, G Coşkun, D Şaker, T Sapmaz… - Ultrastructural …, 2021 - Taylor & Francis
Peripheral nerve injury (PNI) is a major health problem that results in loss of motor and
sensory functions. In treatment of PNI, various methods such as anastomosis, nerve grafts …

Protective effects of alpha lipoic acid on high glucose-induced neurotoxicity in PC12 cells

R Najafi, AM Sharifi, A Hosseini - Metabolic brain disease, 2015 - Springer
Hyperglycemia plays an important role in the development of diabetic neuropathy. In this
study, we investigated the protective effects of alpha lipoic acid (ALA) against high glucose …

A review of the diet, nutrients, and supplementation potential for the outcome augmentation in surgical treatment of peripheral nerve injuries

S Lepić, M Lepić, N Banjanin, S Mandić-Rajčević… - Frontiers in …, 2022 - frontiersin.org
Objective Although the studies have shown the beneficial effects of diet, nutrition, and
supplementation as an independent treatment modality, their roles are underestimated in …

The double-edged sword: effects of pregabalin on experimentally induced sciatic nerve transection and crush injury in rats

M Celik, A Kose, D Kose, E Karakus… - International Journal …, 2015 - Taylor & Francis
Aim: The aim of this study was to research the effects of pregabalin on experimentally
induced peripheral nerve crush injuries in rats. Material and method: Forty-two adult female …

Qian-Zheng-San promotes regeneration after sciatic nerve crush injury in rats

ZY Wang, LH Qin, WG Zhang, PX Zhang… - Neural Regeneration …, 2019 - journals.lww.com
Abstract Qian-Zheng-San, a traditional Chinese prescription consisting of Typhonii Rhizoma,
Bombyx Batryticatus, Scorpio, has been found to play an active therapeutic role in central …

The effect of alpha-lipoic acid on nerve tissue healing after sciatic nerve crush injury in rats

M Yucel, OY Aktas, O Zengi, A Tas, A Tufan, B Eren… - 2023 - annalsmedres.org
Aim: Crush injury damages the nerve, affects its function and causes oxidative stress. Alpha-
lipoic acid (ALA) is an antioxidant agent with protective effects on the nerve tissue. In this …