The rise of the Enterococcus: beyond vancomycin resistance

CA Arias, BE Murray - Nature Reviews Microbiology, 2012 - nature.com
The genus Enterococcus includes some of the most important nosocomial multidrug-
resistant organisms, and these pathogens usually affect patients who are debilitated by …

[HTML][HTML] Pathogenesis and immunity in enterococcal infections

IG Sava, E Heikens, J Huebner - Clinical microbiology and infection, 2010 - Elsevier
Enterococcus faecalis and Enterococcus faecium have emerged as multi-resistant
nosocomial pathogens in immunocompromised and critically ill patients. Multi-resistant …

Native Microbial Colonization of Drosophila melanogaster and Its Use as a Model of Enterococcus faecalis Pathogenesis

CR Cox, MS Gilmore - Infection and immunity, 2007 - Am Soc Microbiol
Enterococci are commensal organisms of the gastrointestinal (GI) tracts of a broad range of
mammalian and insect hosts, but they are also leading causes of nosocomial infection. Little …

Enterococcal infections: host response, therapeutic, and prophylactic possibilities

S Koch, M Hufnagel, C Theilacker, J Huebner - Vaccine, 2004 - Elsevier
The emergence of resistance against multiple antibiotics and the increasing frequency with
which Enterococcus faecalis and Enterococcus faecium are isolated from hospitalized …

Vancomycin-resistant enterococci: therapeutic challenges in the 21st century

WR Miller, BE Murray, LB Rice… - Infectious Disease Clinics, 2016 - id.theclinics.com
The year 1899 saw the first report of the bacterium Micrococcus zymogenes (thought today
to be Enterococcus faecalis) as a cause of infective endocarditis (IE). 1 The patient, a 37 …

Out of the iron age: new insights into the critical role of manganese homeostasis in bacteria

NS Jakubovics, HF Jenkinson - Microbiology, 2001 - microbiologyresearch.org
Manganese (Mn) is required for the growth and survival of most, if not all, living organisms.
Until recently, relatively little was known about how bacteria take up trace nutrients such as …

Characterization of fsr, a Regulator Controlling Expression of Gelatinase and Serine Protease inEnterococcus faecalis OG1RF

X Qin, KV Singh, GM Weinstock… - Journal of bacteriology, 2001 - Am Soc Microbiol
We have previously identified a locus, fsr, a homologue of staphylococcal agr loci, which
positively regulates the expression of gelatinase and serine protease (encoded by gelE and …

Generation and Testing of Mutants of Enterococcus faecalis in a Mouse Peritonitis Model

KV Singh, X Qin, GM Weinstock… - The Journal of infectious …, 1998 - academic.oup.com
A previously described mouse peritonitis model was used to study derivatives of
Enterococcus faecalis strain OG1RF. The addition of sterile rat fecal extracts (SRFE) lowered …

In vivo testing of an Enterococcus faecalis efaA mutant and use of efaA homologs for species identification

KV Singh, TM Coque, GM Weinstock… - FEMS Immunology & …, 1998 - academic.oup.com
Disruption of the previously described efaA (from Enterococcus faecalis antigen A) gene
was generated in E. faecalis strain OG1RF and loss of an∼ 37-kDa immunoreactive band …

Enterococcal virulence

MS Gilmore, PS Coburn… - The enterococci …, 2002 - Wiley Online Library
Studies of the pathogenesis of enterococcal infection are beginning to identify specific
enterococcal and host traits that contribute to the balanced commensal relationship, as well …