Novel insights into immune systems of bats

A Banerjee, ML Baker, K Kulcsar, V Misra… - Frontiers in …, 2020 - frontiersin.org
In recent years, viruses similar to those that cause serious disease in humans and other
mammals have been detected in apparently healthy bats. These include filoviruses …

Towards complete and error-free genome assemblies of all vertebrate species

A Rhie, SA McCarthy, O Fedrigo, J Damas, G Formenti… - Nature, 2021 - nature.com
High-quality and complete reference genome assemblies are fundamental for the
application of genomics to biology, disease, and biodiversity conservation. However, such …

Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates

J Damas, GM Hughes, KC Keough… - Proceedings of the …, 2020 - National Acad Sciences
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the cause of COVID-19. The main receptor of SARS-CoV-2, angiotensin I converting enzyme …

[HTML][HTML] Optimising predictive models to prioritise viral discovery in zoonotic reservoirs

DJ Becker, GF Albery, AR Sjodin, T Poisot… - The Lancet …, 2022 - thelancet.com
Despite the global investment in One Health disease surveillance, it remains difficult and
costly to identify and monitor the wildlife reservoirs of novel zoonotic viruses. Statistical …

Proteomics in non-model organisms: a new analytical frontier

M Heck, BA Neely - Journal of proteome research, 2020 - ACS Publications
For the last century we have relied on model organisms to help understand fundamental
biological processes. Now, with advancements in genome sequencing, assembly, and …

Molecular adaptation and convergent evolution of frugivory in Old World and neotropical fruit bats

K Wang, S Tian, J Galindo‐González… - Molecular …, 2020 - Wiley Online Library
Although cases of independent adaptation to the same dietary niche have been
documented in mammalian ecology, the molecular correlates of such shifts are seldom …

The potential role of endogenous viral elements in the evolution of bats as reservoirs for zoonotic viruses

EC Skirmuntt, M Escalera-Zamudio… - Annual Review of …, 2020 - annualreviews.org
Despite a small genome size, bats have comparable diversity of retroviral and non-retroviral
endogenous sequences to other mammals. These include Class I and Class II retroviral …

Chiropterans are a hotspot for horizontal transfer of DNA transposons in Mammalia

NS Paulat, JM Storer… - Molecular biology …, 2023 - academic.oup.com
Horizontal transfer of transposable elements (TEs) is an important mechanism contributing
to genetic diversity and innovation. Bats (order Chiroptera) have repeatedly been shown to …

Viral CpG deficiency provides no evidence that dogs were intermediate hosts for SARS-CoV-2

DD Pollock, TA Castoe, BW Perry… - Molecular biology …, 2020 - academic.oup.com
Due to the scope and impact of the COVID-19 pandemic there exists a strong desire to
understand where the SARS-CoV-2 virus came from and how it jumped species boundaries …

[PDF][PDF] Long-read sequencing reveals rapid evolution of immunity-and cancer-related genes in bats

A Scheben, O Mendivil Ramos… - Genome biology and …, 2023 - academic.oup.com
Bats are exceptional among mammals for their powered flight, extended lifespans, and
robust immune systems and therefore have been of particular interest in comparative …