[HTML][HTML] Engineering exosomes for targeted drug delivery

Y Liang, L Duan, J Lu, J Xia - Theranostics, 2021 - ncbi.nlm.nih.gov
Exosomes are cell-derived nanovesicles that are involved in the intercellular transportation
of materials. Therapeutics, such as small molecules or nucleic acid drugs, can be …

Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Metal–organic framework-functionalized paper-based electrochemical biosensor for ultrasensitive exosome assay

X Liu, X Gao, L Yang, Y Zhao, F Li - Analytical chemistry, 2021 - ACS Publications
The exosome has emerged as a promising noninvasive biomarker for the early diagnosis of
cancer. Therefore, it is highly desirable to develop simple, inexpensive, and user-friendly …

[HTML][HTML] Exosome engineering: Current progress in cargo loading and targeted delivery

S Fu, Y Wang, X Xia, JC Zheng - NanoImpact, 2020 - Elsevier
Exosomes, a class of small bilayer vesicles derived from virtually all eukaryotic cells, have
been exploited as a promising natural delivery platform due to their low toxicity, excellent …

[HTML][HTML] Exosome nanovesicles: a potential carrier for therapeutic delivery

VP Chavda, A Pandya, L Kumar, N Raval, LK Vora… - Nano Today, 2023 - Elsevier
Exosomes are small nanosized biovesicles that form when multivesicular bodies and the
plasma membrane fuse and are released into the surrounding body fluids. They are best …

Surface functionalization of exosomes for target-specific delivery and in vivo imaging & tracking: Strategies and significance

S Salunkhe, M Basak, D Chitkara, A Mittal - Journal of Controlled …, 2020 - Elsevier
Exosomes are natural nanovesicles excreted by many cells for intercellular communication
and for transfer of materials including proteins, nucleic acids and even synthetic therapeutic …

Potential use of exosomes as diagnostic biomarkers and in targeted drug delivery: progress in clinical and preclinical applications

MN Huda, M Nafiujjaman, IG Deaguero… - ACS biomaterials …, 2021 - ACS Publications
Exosomes are cell-derived vesicles containing heterogeneous active biomolecules such as
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …

Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers

C Liu, J Zhao, F Tian, L Cai, W Zhang, Q Feng… - Nature biomedical …, 2019 - nature.com
Non-invasive assays for early cancer screening are hampered by challenges in the isolation
and profiling of circulating biomarkers. Here, we show that surface proteins from serum …

Aptamer/AuNP biosensor for colorimetric profiling of exosomal proteins

Y Jiang, M Shi, Y Liu, S Wan, C Cui… - Angewandte Chemie …, 2017 - Wiley Online Library
Exosomes constitute an emerging biomarker for cancer diagnosis because they carry
multiple proteins that reflect the origins of parent cells. Assessing exosome surface proteins …

Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612

L Ge, C Xun, W Li, S Jin, Z Liu, Y Zhuo, D Duan… - Journal of …, 2021 - Springer
Mesenchymal stem cells (MSCs) play important roles in tissue repair and regeneration, such
as the induction of angiogenesis, particularly under hypoxic conditions. However, the …