S Miyamoto, N Miyake, LF Jarskog… - Molecular …, 2012 - nature.com
Since the introduction of chlorpromazine and throughout the development of the new- generation antipsychotic drugs (APDs) beginning with clozapine, the D 2 receptor has been …
I Laszlovszky, Á Barabássy, G Németh - Advances in Therapy, 2021 - Springer
Schizophrenia is characterized by positive, negative, cognitive, and affective symptoms. Antipsychotic medications, which work by blocking the dopamine D 2 receptor, are the …
J Volavka, L Citrome - Schizophrenia bulletin, 2011 - academic.oup.com
Schizophrenia elevates the risk for aggressive behavior and violent crime, and different approaches have been used to manage this problem. The results of such treatments vary …
Olanzapine is a second-generation atypical antipsychotic with proven efficacy for the treatment of schizophrenia. Approved in 1996, olanzapine is one of the most studied …
MX Patel, FN Sethi, TRE Barnes, R Dix… - Journal of …, 2018 - ingentaconnect.com
The British Association for Psychopharmacology and the National Association of Psychiatric Intensive Care and Low Secure Units developed this joint evidence-based consensus …
BACKGROUND: To optimize the management of patients with schizophrenia, quantification of treatment effects is crucial. While in research studies, the use of quantitative assessments …
S Marder, WW Fleischhacker, W Earley, K Lu… - European …, 2019 - Elsevier
Schizophrenia affects various symptom domains, including positive and negative symptoms, mood, and cognition. Cariprazine, a dopamine D 3/D 2 receptor partial agonist and …
K Komossa, C Rummel‐Kluge… - Cochrane Database …, 2009 - cochranelibrary.com
Background In many countries of the industrialised world second generation ('atypical') antipsychotics have become the first line drug treatment for people with schizophrenia. The …