In many organisms, cytochrome P450 enzymes are the primary detoxifying enzymes.
Enhanced P450 activity can be mediated by the emergence of new genes, increased …

Metabolic mechanisms conferring pyrethroid resistance in malaria vectors are jeopardizing
the effectiveness of insecticide-based interventions, and identification of their markers is a …

Myosin storage myopathy (MSM) is a rare skeletal muscle disorder caused by mutations in
the slow muscle/β-cardiac myosin heavy chain (MHC) gene. MSM missense mutations …

The overexpression and overactivity of key cytochrome P450s (CYP450) genes are major
drivers of metabolic resistance to insecticides in African malaria vectors such as Anopheles …

Assessing the genetic diversity of metabolic resistance genes, such as cytochrome P450s,
helps to understand the dynamics and evolution of resistance in the field. Here, we analyzed …

Background There are several indications that pesticides used in agriculture contribute to
the emergence and spread of resistance of mosquitoes to vector control insecticides …

Assessing the genetic diversity of metabolic resistance genes, such as cytochrome P450s,
helps to understand the dynamics and evolution of resistance in the field. Here, we analyzed …

In their whole life, insects deal with many toxic substances that can be natural as well as
many agrochemicals like insecticides. Gene regulation is often the main cause of insecticide …

Insecticide resistance in malaria vector populations poses a major threat to malaria control,
which relies largely on insecticidal interventions. Contemporary vector-control strategies …