Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond

Y Lee, E Puumala, N Robbins, LE Cowen - Chemical reviews, 2020 - ACS Publications
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …

The Fungal Cell Wall: Candida, Cryptococcus, and Aspergillus Species

R Garcia-Rubio, HC de Oliveira, J Rivera… - Frontiers in …, 2020 - frontiersin.org
The fungal cell wall is located outside the plasma membrane and is the cell compartment
that mediates all the relationships of the cell with the environment. It protects the contents of …

Structural and mechanistic insights into fungal β-1, 3-glucan synthase FKS1

X Hu, P Yang, C Chai, J Liu, H Sun, Y Wu, M Zhang… - Nature, 2023 - nature.com
The membrane-integrated synthase FKS is involved in the biosynthesis of β-1, 3-glucan, the
core component of the fungal cell wall,. FKS is the target of widely prescribed antifungal …

Regulation and function of defense-related callose deposition in plants

Y Wang, X Li, B Fan, C Zhu, Z Chen - International Journal of Molecular …, 2021 - mdpi.com
Plants are constantly exposed to a wide range of potential pathogens and to protect
themselves, have developed a variety of chemical and physical defense mechanisms …

[HTML][HTML] Cell wall glucans of fungi. A review

J Ruiz-Herrera, L Ortiz-Castellanos - The Cell Surface, 2019 - Elsevier
Glucans are the most abundant polysaccharides in the cell walls of fungi, and their
structures are highly variable. Accordingly, their glucose moieties may be joined through …

Regulation of Cell Wall Biogenesis in Saccharomyces cerevisiae: The Cell Wall Integrity Signaling Pathway

DE Levin - Genetics, 2011 - academic.oup.com
The yeast cell wall is a strong, but elastic, structure that is essential not only for the
maintenance of cell shape and integrity, but also for progression through the cell cycle …

Fungal cell wall: emerging antifungals and drug resistance

SL Lima, AL Colombo… - Frontiers in microbiology, 2019 - frontiersin.org
The cell wall is an essential component in fungal homeostasis. The lack of a covering wall in
human cells makes this component an attractive target for antifungal development. The host …

Architecture and Biosynthesis of the Saccharomyces cerevisiae Cell Wall

P Orlean - Genetics, 2012 - academic.oup.com
The wall gives a Saccharomyces cerevisiae cell its osmotic integrity; defines cell shape
during budding growth, mating, sporulation, and pseudohypha formation; and presents …

Small GTP-binding proteins

Y Takai, T Sasaki, T Matozaki - Physiological reviews, 2001 - journals.physiology.org
Small GTP-binding proteins (G proteins) exist in eukaryotes from yeast to human and
constitute a superfamily consisting of more than 100 members. This superfamily is …

The structure and synthesis of the fungal cell wall

SM Bowman, SJ Free - Bioessays, 2006 - Wiley Online Library
The fungal cell wall is a dynamic structure that protects the cell from changes in osmotic
pressure and other environmental stresses, while allowing the fungal cell to interact with its …