Beyond the beat: A pioneering investigation into exercise modalities for alleviating diabetic cardiomyopathy and enhancing cardiac health

AR Khan, MAH Alnoud, H Ali, I Ali, S Ahmad… - Current Problems in …, 2023 - Elsevier
Patients with preexisting cardiovascular disease or those at high risk for developing the
condition are often offered exercise as a form of therapy. Patients with cancer who are at an …

Nanotherapeutic approaches for transdermal drug delivery systems and their biomedical applications

SU Khan, M Ullah, S Saeed, EAM Saleh… - European Polymer …, 2024 - Elsevier
Transdermal drug delivery systems (TDDS) are designed to deliver drugs through the skin
and into the systemic circulation. They offer several advantages over traditional oral or …

Tumor-associated macrophages: Potential therapeutic targets and diagnostic markers in cancer

J Song, T Xiao, M Li, Q Jia - Pathology-Research and Practice, 2023 - Elsevier
Macrophages are plastic and functionally diverse, present in all tissues, and play a key role
in organisms from development, homeostasis and repair, to immune responses to …

Mechanism-driven design of multispecific antibodies for targeted disease treatment

J Fine, B Meksiriporn, J Tan… - Annual Review of …, 2024 - annualreviews.org
Antibody-based therapeutics constitute a rapidly growing class of pharmaceutical
compounds. However, monoclonal antibodies, which specifically engage only one target …

Unraveling the enigma of tumor-associated macrophages: challenges, innovations, and the path to therapeutic breakthroughs

S Shao, H Miao, W Ma - Frontiers in Immunology, 2023 - frontiersin.org
Tumor-associated macrophages (TAMs) are integral to the tumor microenvironment (TME),
influencing cancer progression significantly. Attracted by cancer cell signals, TAMs exhibit …

[HTML][HTML] Nanocarrier-based targeting of metabolic pathways for endometrial cancer: Status and future perspectives

Y Wang, S Chen, C Wang, F Guo - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cancer is the second-most lethal global disease, as per health reports, and is responsible
for around 70% of deaths in low-and middle-income countries. Endometrial cancer is one of …

Heartfelt living: deciphering the link between lifestyle choices and cardiovascular vitality

X Jiang, MAH Alnoud, H Ali, I Ali, T Hussain… - Current Problems in …, 2024 - Elsevier
Cardiovascular diseases (CVDs) are still leading to a significant number of deaths
worldwide despite the remarkable advancements in medical technology and pharmacology …

High infiltration of CD209+ dendritic cells and CD163+ macrophages in the peritumor area of prostate cancer is predictive of late adverse outcomes

OE Molina, H LaRue, D Simonyan… - Frontiers in …, 2023 - frontiersin.org
Introduction Prostate cancer (PCa) shows considerable variation in clinical outcomes
between individuals with similar diseases. The initial host-tumor interaction as assessed by …

Boron Dipyrromethene-Based Nanotheranostic System for Sonophotoassisted Therapy and Simultaneous Monitoring of Tumor Immune Microenvironment …

X Li, X Sun, H Chen, Y Wang, H Chen, Y Gao - ACS nano, 2024 - ACS Publications
Therapy-induced modulation of the tumor microenvironment (TME) to overcome the
immunosuppressive TME is considered to be an opportunity for cancer treatment. However …

Immunotherapy and the ovarian cancer microenvironment: Exploring potential strategies for enhanced treatment efficacy

ZB Wang, X Zhang, C Fang, XT Liu, QJ Liao… - …, 2024 - Wiley Online Library
Despite progress in cancer immunotherapy, ovarian cancer (OC) prognosis continues to be
disappointing. Recent studies have shed light on how not just tumour cells, but also the …