Are fibrinaloid microclots a cause of autoimmunity in Long Covid and other post-infection diseases?

DB Kell, E Pretorius - Biochemical Journal, 2023 - portlandpress.com
It is now well established that the blood-clotting protein fibrinogen can polymerise into an
anomalous form of fibrin that is amyloid in character; the resultant clots and microclots entrap …

MIRRAGGE–minimum information required for reproducible AGGregation experiments

PM Martins, S Navarro, A Silva, MF Pinto… - Frontiers in molecular …, 2020 - frontiersin.org
Reports on phase separation and amyloid formation for multiple proteins and aggregation-
prone peptides are recurrently used to explore the molecular mechanisms associated with …

[HTML][HTML] An ultra-sensitive dopamine measurement platform based on molecularly imprinted polymer-carbon hybrid nanomaterials for in vitro use

K Nekoueian, M Akhoundian, N Wester, T Laurila - Electrochimica Acta, 2023 - Elsevier
In the present study, we designed an ultrasensitive sensing platform for the evaluation of the
physiologically relevant values of basal dopamine (DA) in a culture medium as a complex …

Role of charged residues of the “electrostatic loop” of hSOD1 in promotion of aggregation: Implications for the mechanism of ALS-associated mutations under …

E Mavadat, B Seyedalipour, S Hosseinkhani… - International Journal of …, 2023 - Elsevier
Protein misfolding and amyloid formation are hallmarks of numerous diseases, including
amyotrophic lateral sclerosis (ALS), in which hSOD1 aggregation is involved in …

Laser emission of thioflavin T uncovers protein aggregation in amyloid nucleation phase

P Hanczyc, P Fita - ACS photonics, 2021 - ACS Publications
There is currently no definitive test for early detection of neurodegeneration which is linked
with protein aggregation. Finding methods capable of detecting intermediate states of …

Amyloid-like aggregation influenced by lead (II) and cadmium (II) ions in hen egg white ovalbumin

N Mijin, J Milošević, S Stevanović, P Petrović, A Lolić… - Food …, 2023 - Elsevier
The aggregation of proteins into fibrillar, amyloid-like aggregates generally results in an
improved, positive effect on various techno-functional properties within food products, such …

Distribution and relative abundance of S100 proteins in the brain of the APP23 Alzheimer's disease model mice

S Hagmeyer, MA Romão, JS Cristóvão… - Frontiers in …, 2019 - frontiersin.org
Increasing evidence links proteins of the S100 family to the pathogenesis of Alzheimer's
disease (AD). S100 proteins are EF-hand calcium-binding proteins with intra-and …

Exploring the potential of infrared spectroscopy in qualitative and quantitative monitoring of ovalbumin amyloid fibrillation

J Milošević, J Petrić, B Jovčić, B Janković… - Spectrochimica Acta Part …, 2020 - Elsevier
Amyloid fibrils are highly ordered self-assembled (poly) peptide aggregates with cross-β
structural pattern. Ovalbumin was used as a model for exploring the potential of infrared …

[图书][B] Protein folding: An introduction

CM Gomes, PFN Faísca, CM Gomes, PFN Faísca - 2019 - Springer
We have come a long way since coining of the term protein and the early findings that
proteins are charged macromolecules composed of strings of amino acids linked by peptide …

Detection of insulin oligomeric forms by a novel surface plasmon resonance‐diffusion coefficient based approach

D Calcagno, ML Perina, GA Zingale, I Pandino… - Protein …, 2024 - Wiley Online Library
Insulin is commonly used to treat diabetes and undergoes aggregation at the site of
repeated injections in diabetic patients. Moreover, aggregation is also observed during its …