Atherosclerosis is nowadays generally accepted as an inflammatory disease. It is known that
local inflammation occurs in the formation the plaques, as macrophages and other immuno …

Introduction Neutrophils are the key cells of our innate immune system with a primary role in
host defense. They rapidly arrive at the site of infection and display a range of effector …

Continuous diagnostic tests are often used for discriminating between healthy and diseased
populations. For the clinical application of such tests, it is useful to select a cutpoint or …

Background Inflammation associated with acute myocardial infarction (AMI) is frequently
marked by a peripheral leukocytosis and relative neutrophilia. Whether this process may …

Type 1 diabetes is an autoimmune disease that afflicts millions of people worldwide. It
occurs as the consequence of destruction of insulin‐producing pancreatic β‐cells triggered …

The present invention provides methods for the identification and use of diagnostic markers
for differential diagnosis of diseases. In a various aspects, the invention relates to methods …

The present invention relates to methods for the diagnosis and evaluation of acute coronary
syndromes. In particular, patient test samples are analyzed for the presence and amount of …

1. Introduction myocardial ischemia. If the concept of a causative role of inflammation,
especially PMN accumulation and activa-The presence of inflammatory cells in the ischemic …

BACKGROUND: Thoracic aortic dissection (TAD) is a life-threatening aortic disease without
effective medical treatment. Increasing evidence has suggested a role for NE (neutrophil …

In clinical and epidemiological studies, biomarkers are associated with disease diagnosis
and prognosis. Using biomarkers to classify subjects into groups, such as high-risk or low …