Cell-size control
AA Amodeo, JM Skotheim - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Cells of a given type maintain a characteristic cell size to function efficiently in their
ecological or organismal context. They achieve this through the regulation of growth rates or …
ecological or organismal context. They achieve this through the regulation of growth rates or …
[HTML][HTML] Translate to divide: сontrol of the cell cycle by protein synthesis
M Polymenis, R Aramayo - Microbial Cell, 2015 - ncbi.nlm.nih.gov
Protein synthesis underpins much of cell growth and, consequently, cell multiplication.
Understanding how proliferating cells commit and progress into the cell cycle requires …
Understanding how proliferating cells commit and progress into the cell cycle requires …
Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules
RNA-protein (RNP) granules have been proposed to assemble by forming solid RNA/protein
aggregates or through phase separation into a liquid RNA/protein phase. Which model …
aggregates or through phase separation into a liquid RNA/protein phase. Which model …
Measurement of average decoding rates of the 61 sense codons in vivo
Most amino acids can be encoded by several synonymous codons, which are used at
unequal frequencies. The significance of unequal codon usage remains unclear. One …
unequal frequencies. The significance of unequal codon usage remains unclear. One …
Dissimilation of synonymous codon usage bias in virus–host coevolution due to translational selection
F Chen, P Wu, S Deng, H Zhang, Y Hou, Z Hu… - Nature ecology & …, 2020 - nature.com
Eighteen of the 20 amino acids are each encoded by more than one synonymous codon.
Due to differential transfer RNA supply within the cell, synonymous codons are not used with …
Due to differential transfer RNA supply within the cell, synonymous codons are not used with …
Polysome propensity and tunable thresholds in coding sequence length enable differential mRNA stability
The half-life of mRNAs, as well as their translation, increases in proportion to the optimal
codons, indicating a tight coupling of codon-dependent differential translation and …
codons, indicating a tight coupling of codon-dependent differential translation and …
Differential scaling of gene expression with cell size may explain size control in budding yeast
Yeast cells must grow to a critical size before committing to division. It is unknown how size
is measured. We find that as cells grow, mRNAs for some cell-cycle activators scale faster …
is measured. We find that as cells grow, mRNAs for some cell-cycle activators scale faster …
Cis-regulatory elements explain most of the mRNA stability variation across genes in yeast
The stability of mRNA is one of the major determinants of gene expression. Although a
wealth of sequence elements regulating mRNA stability has been described, their …
wealth of sequence elements regulating mRNA stability has been described, their …
Context-dependent deposition and regulation of mRNAs in P-bodies
Cells respond to stress by remodeling their transcriptome through transcription and
degradation. Xrn1p-dependent degradation in P-bodies is the most prevalent decay …
degradation. Xrn1p-dependent degradation in P-bodies is the most prevalent decay …
GWIPS-viz: 2018 update
AM Michel, SJ Kiniry, PBF O'Connor… - Nucleic acids …, 2018 - academic.oup.com
The GWIPS-viz browser (http://gwips. ucc. ie/) is an on-line genome browser which is
tailored for exploring ribosome profiling (Ribo-seq) data. Since its publication in 2014 …
tailored for exploring ribosome profiling (Ribo-seq) data. Since its publication in 2014 …