GSK3: A potential target and pending issues for treatment of Alzheimer's disease
J Zhao, M Wei, M Guo, M Wang, H Niu… - CNS Neuroscience & …, 2024 - Wiley Online Library
Abstract Glycogen synthase kinase‐3 (GSK3), consisting of GSK3α and GSK3β subtypes, is
a complex protein kinase that regulates numerous substrates. Research has observed …
a complex protein kinase that regulates numerous substrates. Research has observed …
Emerging role of adaptive immunity in diabetes-induced cognitive impairment: from the periphery to the brain
G Yang, R Su, J Bu, Y Li, X Lin, J Jin, Y Zhang… - Metabolic Brain …, 2025 - Springer
Diabetic cognitive impairment (DCI) is a central nervous system complication induced by
peripheral metabolic dysfunction of diabetes mellitus. Cumulative studies have shown that …
peripheral metabolic dysfunction of diabetes mellitus. Cumulative studies have shown that …
Identification of JAZF1, KNOP1, and PLEKHA1 as causally associated genes and drug targets for Alzheimer's disease: a summary data-based Mendelian …
Y Zhai, N Li, Y Zhang, H Li, L Wu, C Wei, J Ji… - …, 2024 - Springer
Background There is a growing body of evidence indicating the significant role of the
immune system and immune cells in the progression of Alzheimer's disease (AD). However …
immune system and immune cells in the progression of Alzheimer's disease (AD). However …
Alzheimer's disease and the immune system: the emerging role of TEMRA cells
ED Winford, AD Bachstetter - Neural Regeneration Research, 2025 - journals.lww.com
Alzheimer's disease (AD) is the most common form of dementia, affecting millions
worldwide. It is characterized by progressive cognitive decline and changes in behavior and …
worldwide. It is characterized by progressive cognitive decline and changes in behavior and …
CytoNormPy enables a fast and scalable removal of batch effects in cytometry datasets.
T Exner, NS Hackert, L Leomazzi, S Van Gassen… - bioRxiv, 2024 - biorxiv.org
Motivation: We present a python implementation of the widely used CytoNorm algorithm for
the removal of batch effects. Results Our implementation ran up to 85% faster than its R …
the removal of batch effects. Results Our implementation ran up to 85% faster than its R …