Epidemiological surveys indicate that the incidence of inflammatory bowel disease (IBD) is
increasing rapidly with the continuous growth of the economy. A large number of studies …

Inflammatory bowel disease (IBD) is a chronic and life‐threating inflammatory disease of
gastroenteric tissue characterized by episodes of intestinal inflammation. The pathogenesis …

Understanding complex tissues requires single-cell deconstruction of gene regulation with
precision and scale. Here, we assess the performance of a massively parallel droplet-based …

Innate immunity is maintained in part by antigen presenting cells (APCs) including dendritic
cells, macrophages, and B cells. APCs interact with T cells to link innate and adaptive …

Antigen-presenting cells (APCs) are master regulators of the immune response by directly
interacting with T cells to orchestrate distinct functional outcomes. Several types of …

The barrier surfaces of the gastrointestinal tract are in constant contact with various
microorganisms. Cytokines orchestrate the mucosal adaptive and innate immune cells in the …

Innate lymphoid cells (ILCs) are innate counterparts of T cells that contribute to immune
responses by secreting effector cytokines and regulating the functions of other innate and …

Innate lymphoid cells (ILCs) are enriched at barrier surfaces of the mammalian body where
they rapidly respond to host, microbial or environmental stimuli to promote immunity or …

The trillions of microorganisms in the gut microbiome have attracted much attention recently
owing to their sophisticated and widespread impacts on numerous aspects of host …

The multifaceted organization of the immune system involves not only patrolling
lymphocytes that constantly monitor antigen-presenting cells in secondary lymphoid organs …