Purpose To make recommendations regarding the use of bisphosphonates and other bone-
modifying agents as adjuvant therapy for patients with breast cancer. Methods Cancer Care …

Breast cancer is the second greatest cause of death among women worldwide; it comprises
a group of heterogeneous diseases that evolves due to uncontrolled cellular growth and …

R-Aminophosphonic acids are broadly defined as analogues of amino acids in which the
carboxylic group is replaced by a phosphonic acid or related group (usually phosphonous or …

Background Bisphosphonates are specific inhibitors of osteoclastic activity and used in the
treatment of patients with multiple myeloma (MM). While bisphosphonates are shown to be …

The adverse events of the nitrogen-containing bisphosphonates are reviewed. Oral
bisphosphonates (alendronate, risedronate and ibandronate), mainly used for the treatment …

Hypercalcemia of malignancy affects up to one in five cancer patients during the course of
their disease. It is associated with both liquid malignancies, commonly multiple myeloma …

Abstract α, α-Bisphosphonates (BPs) are well established in the treatment of bone diseases
such as osteoporosis and Paget's disease. Their successful application originates from their …

Since their discovery over 100years ago, bisphosphonates have been used industrially as
corrosion inhibitors and complexing agents. With the discovery of their pharmacological …

Necrotic bone exposure in the oral cavity has recently been reported in patients treated with
nitrogen‐containing bisphosphonates as part of their therapeutic regimen for multiple …

Oncologic emergencies can occur at any time during the course of a malignancy, from the
presenting symptom to end‐stage disease. Although some of these conditions are related to …