Accelerated immune ageing is associated with COVID-19 disease severity

JM Lord, T Veenith, J Sullivan, A Sharma-Oates… - Immunity & …, 2024 - Springer
Background The striking increase in COVID-19 severity in older adults provides a clear
example of immunesenescence, the age-related remodelling of the immune system. To …

Large-scale whole-exome sequencing analyses identified protein-coding variants associated with immune-mediated diseases in 350,770 adults

L Yang, YN Ou, BS Wu, WS Liu, YT Deng… - Nature …, 2024 - nature.com
The genetic contribution of protein-coding variants to immune-mediated diseases (IMDs)
remains underexplored. Through whole exome sequencing of 40 IMDs in 350,770 UK …

Risk of death, thrombotic and hemorrhagic events in anticoagulated patients with atrial fibrillation and systemic autoimmune diseases: an analysis from a global …

T Bucci, C Cardamone, M Triggiani, PRJ Ames… - Clinical Research in …, 2024 - Springer
Background Growing evidence showing that systemic autoimmune diseases (SADs) are
associated with a high risk of atrial fibrillation (AF). However, the impact of SAD on the …

Lupus and other autoimmune diseases: epidemiology in the population of African ancestry, and diagnostic and management challenges in Africa

M Essouma, JJ Noubiap - Journal of Allergy and Clinical Immunology …, 2024 - Elsevier
Autoimmune diseases are prevalent among people of African ancestry living outside of
Africa. However, the burden of autoimmune diseases in Africa is not well understood. This …

The emergence of common health conditions across the life course: evidence from the Born in Bradford family cohort

G Santorelli, D Lewer… - Wellcome Open …, 2024 - wellcomeopenresearch.org
Background Born in Bradford (BiB) is a family cohort study with linked routine health records.
We calculated the rates of common health conditions and explored differences between …

Enhanced immune ageing associated with increasing COVID-19 disease severity

J Lord, T Veenith, J Sullivan, A Oates, A Richter… - 2023 - researchsquare.com
Background The striking increase in COVID-19 severity in older adults provides a clear
example of immunesenescence, the age-related remodelling of the immune system. To …

Autoimmune Disorders Reported Following COVID-19 Vaccination: A Disproportionality Analysis Using the WHO VigiBase

S Kim, S Bea, SA Choe, NK Choi, JY Shin - 2023 - researchsquare.com
Purpose: Owing to autoimmune disorders (AIDs) and coronavirus disease (COVID-19)
vaccines sharing common biological mechanisms, identifying the risk of AIDs associated …

Risk of Death, Thrombotic and Hemorrhagic Events in Patients with Atrial Fibrillation and Systemic Autoimmune Diseases. An Analysis from a Global Federated …

T Bucci, C Cardamone, M Triggiani, PRJ Ames… - An Analysis from a … - papers.ssrn.com
Background: Growing evidence showing that systemic autoimmune diseases (SAD) are
associated with a high risk of atrial fibrillation (AF). However, the impact of SAD on the …

[PDF][PDF] 犬の慢性腸症の好発品種とMHC クラスII 遺伝子型に関する研究

中澤慈 - 2023 - nihon-u.repo.nii.ac.jp
犬の慢性腸症は慢性的な消化器症状を示す疾患であるが, 病態は不明なことが多い.
治療に免疫抑制剤などの投与で改善する例が多いなどから免疫学的な関与が疑われている …