Anthracycline-induced cardiotoxicity

ALA Ferreira, LS Matsubara… - … Agents in Medicinal …, 2008 - ingentaconnect.com
The anthracyclines constitute a group of drugs widely used for the treatment of a variety of
human tumors. However, the development of irreversible cardiotoxicity has limited their use …

[HTML][HTML] Prevention of the postthrombotic syndrome with anticoagulation: a narrative review

I Makedonov, SR Kahn, J Abdulrehman… - Thrombosis and …, 2022 - thieme-connect.com
The postthrombotic syndrome (PTS) is chronic venous insufficiency secondary to a prior
deep vein thrombosis (DVT). It is the most common complication of venous …

Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis

RA Shaker, SH Abboud, HC Assad, N Hadi - BMC Pharmacology and …, 2018 - Springer
Background Doxorubicin (DOX) is commonly used in the treatment of many types of cancers
but its cardiotoxicity is limiting its clinical use. Beyond its anticoagulant action, enoxaparin …

2-Mercaptoethane sulfonate prevents doxorubicin-induced plasma protein oxidation and TNF-α release: implications for the reactive oxygen species-mediated …

CD Aluise, S Miriyala, T Noel, R Sultana… - Free Radical Biology …, 2011 - Elsevier
Doxorubicin (DOX), an anthracycline used to treat a variety of cancers, is known to generate
intracellular reactive oxygen species. Moreover, many patients who have undergone …

Resveratrol treatment protects against doxorubicin-induced cardiotoxicity by alleviating oxidative damage

E Tatlidede, Ö Şehirli, A Velioğlu-Öğünç… - Free radical …, 2009 - Taylor & Francis
The possible protective effects of resveratrol (RVT) against cardiotoxicity were investigated
in Wistar albino rats treated with saline, saline+ doxorubicin (DOX; 20 mg/kg) or RVT (10 …

d-limonene suppresses doxorubicin-induced oxidative stress and inflammation via repression of COX-2, iNOS, and NFκB in kidneys of Wistar rats

MU Rehman, M Tahir, AQ Khan… - Experimental …, 2014 - journals.sagepub.com
d-limonene is a naturally occurring monoterpene and has been found to posses numerous
therapeutic properties. In this study, we used d-limonene as a protective agent against the …

[HTML][HTML] Pea (Pisum sativum) peel extract attenuates DOX-induced oxidative myocardial injury

EA Abdelghffar, WA Obaid, AM Elgamal… - Biomedicine & …, 2021 - Elsevier
The goal of this work aimed to evaluate the protective effects of pea (Pisum sativum) peels
extract versus doxorubicin-induced oxidative myocardial injury in male mice. The mice were …

Doxorubicin-induced in vivo nephrotoxicity involves oxidative stress-mediated multiple pro-and anti-apoptotic signaling pathways

TS Lahoti, D Patel, V Thekkemadom… - Current …, 2012 - ingentaconnect.com
Doxorubicin (DOX), a prominent anticancer agent has enjoyed considerable popularity in
the last few decades because of its usefulness in the management of various forms of …

Doxorubicin-induced vascular toxicity–targeting potential pathways may reduce procoagulant activity

I Ben Aharon, H Bar Joseph, M Tzabari, B Shenkman… - PLoS …, 2013 - journals.plos.org
Introduction Previous study in mice using real-time intravital imaging revealed an acute
deleterious effect of doxorubicin (DXR) on the gonadal vasculature, as a prototype of an end …

Tomato-oleoresin supplement prevents doxorubicin-induced cardiac myocyte oxidative DNA damage in rats

ALA Ferreira, DMF Salvadori… - … /Genetic Toxicology and …, 2007 - Elsevier
Doxorubicin (DOX) is an efficient chemotherapeutic agent used against several types of
tumors; however, its use is limited due to severe cardiotoxicity. Since it is accepted that …