LncRNA: Shedding light on mechanisms and opportunities in fibrosis and aging

Z Yang, S Jiang, J Shang, Y Jiang, Y Dai, B Xu… - Ageing research …, 2019 - Elsevier
Fibrosis is universally observed in multiple aging-related diseases and progressions and is
characterized by excess accumulation of the extracellular matrix. Fibrosis occurs in various …

Molecular mechanisms of skeletal muscle hypertrophy

S Schiaffino, C Reggiani, T Akimoto… - Journal of …, 2021 - content.iospress.com
Skeletal muscle hypertrophy can be induced by hormones and growth factors acting directly
as positive regulators of muscle growth or indirectly by neutralizing negative regulators, and …

Functions and regulatory mechanisms of lncRNAs in skeletal myogenesis, muscle disease and meat production

S Wang, J Jin, Z Xu, B Zuo - Cells, 2019 - mdpi.com
Myogenesis is a complex biological process, and understanding the regulatory network of
skeletal myogenesis will contribute to the treatment of human muscle related diseases and …

Non-coding RNA regulates the myogenesis of skeletal muscle satellite cells, injury repair and diseases

Y Zhao, M Chen, D Lian, Y Li, Y Li, J Wang, S Deng… - Cells, 2019 - mdpi.com
Skeletal muscle myogenesis and injury-induced muscle regeneration contribute to muscle
formation and maintenance. As myogenic stem cells, skeletal muscle satellite cells have the …

Involvements of long noncoding RNAs in obesity‐associated inflammatory diseases

SN Wijesinghe, T Nicholson, K Tsintzas… - Obesity …, 2021 - Wiley Online Library
Obesity is associated with chronic low‐grade inflammation that affects the phenotype of
multiple tissues and therefore is implicated in the development and progression of several …

Ubiquitin ligases at the heart of skeletal muscle atrophy control

D Peris-Moreno, L Cussonneau, L Combaret, C Polge… - Molecules, 2021 - mdpi.com
Skeletal muscle loss is a detrimental side-effect of numerous chronic diseases that
dramatically increases mortality and morbidity. The alteration of protein homeostasis is …

The functional role of long non-coding RNA in myogenesis and skeletal muscle atrophy

K Hitachi, M Honda, K Tsuchida - Cells, 2022 - mdpi.com
Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis.
Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass …

Role of MicroRNAs and long non-coding RNAs in sarcopenia

J Lee, H Kang - Cells, 2022 - mdpi.com
Sarcopenia is an age-related pathological process characterized by loss of muscle mass
and function, which consequently affects the quality of life of the elderly. There is growing …

A novel long non-coding RNA Myolinc regulates myogenesis through TDP-43 and Filip1

G Militello, MR Hosen, Y Ponomareva… - Journal of molecular …, 2018 - academic.oup.com
Myogenesis is a complex process required for skeletal muscle formation during embryonic
development and for regeneration and growth of myofibers in adults. Accumulating evidence …

Skeletal muscle properties show collagen organization and immune cell content are associated with resistance exercise response heterogeneity in older persons

DE Long, BD Peck, KM Lavin… - Journal of Applied …, 2022 - journals.physiology.org
In older individuals, hypertrophy from progressive resistance training (PRT) is compromised
in approximately one-third of participants in exercise trials. The objective of this study was to …