The detection of acute HIV infection

MS Cohen, CL Gay, MP Busch… - The Journal of infectious …, 2010 - academic.oup.com
Acute human immunodeficiency virus (HIV) infection (AHI) can be defined as the time from
HIV acquisition until seroconversion. Incident HIV infection is less well defined but …

Recent levels and trends in HIV incidence rates among adolescent girls and young women in ten high-prevalence African countries: a systematic review and meta …

I Birdthistle, C Tanton, A Tomita, K de Graaf… - The Lancet Global …, 2019 - thelancet.com
Background The roll-out of antiretroviral therapy (ART) has changed contexts of HIV risk, but
the influence on HIV incidence among young women is not clear. We aimed to summarise …

[HTML][HTML] Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: the Global Burden of Disease Study 2015

H Wang, TM Wolock, A Carter, G Nguyen, HH Kyu… - The lancet HIV, 2016 - thelancet.com
Background Timely assessment of the burden of HIV/AIDS is essential for policy setting and
programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD …

Disease ecology meets ecological immunology: understanding the links between organismal immunity and infection dynamics in natural populations

DM Hawley, SM Altizer - Functional Ecology, 2011 - Wiley Online Library
Ecological immunology and disease ecology are two relatively young disciplines that apply
ecological approaches and principles to traditionally non‐ecological fields. In both cases, an …

Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection

J Ananworanich, A Schuetz, C Vandergeeten, I Sereti… - PloS one, 2012 - journals.plos.org
Background Limited knowledge exists on early HIV events that may inform preventive and
therapeutic strategies. This study aims to characterize the earliest immunologic and virologic …

Detection of recent HIV-1 infection using a new limiting-antigen avidity assay: potential for HIV-1 incidence estimates and avidity maturation studies

YT Duong, M Qiu, AK De, K Jackson, T Dobbs, AA Kim… - PloS one, 2012 - journals.plos.org
Background Accurate and reliable laboratory methods are needed for estimation of HIV-1
incidence to identify the high-risk populations and target and monitor prevention efforts. We …

Declining HIV incidence in sub‐Saharan Africa: a systematic review and meta‐analysis of empiric data

K Joshi, J Lessler, O Olawore… - African Journal of …, 2021 - journals.lww.com
Introduction: UNAIDS models suggest HIV incidence is declining in sub-Saharan Africa. The
objective of this study was to assess whether modelled trends are supported by empirical …

Beyond detuning: 10 years of progress and new challenges in the development and application of assays for HIV incidence estimation

MP Busch, CD Pilcher, TD Mastro, J Kaldor… - Aids, 2010 - journals.lww.com
In the ongoing battle against HIV/AIDS, it is critical that we are able to measure and monitor
HIV incidence, that is the number of new infections during a period of time, usually …

Recalibration of the limiting antigen avidity EIA to determine mean duration of recent infection in divergent HIV-1 subtypes

YT Duong, R Kassanjee, A Welte, M Morgan, A De… - PloS one, 2015 - journals.plos.org
Background Mean duration of recent infection (MDRI) and misclassification of long-term HIV-
1 infections, as proportion false recent (PFR), are critical parameters for laboratory-based …

Association of the ANRS-12126 male circumcision project with HIV levels among men in a South African township: evaluation of effectiveness using cross-sectional …

B Auvert, D Taljaard, D Rech, P Lissouba… - PLoS …, 2013 - journals.plos.org
Background Randomized controlled trials have shown that voluntary medical male
circumcision (VMMC) reduces HIV infection by 50% to 60% in sub-Saharan African …