Abstract The Wisconsin Registry for Alzheimer's Prevention is a longitudinal observational
cohort study enriched with persons with a parental history (PH) of probable Alzheimer's …

Regulated cell death (RCD) is an ordered and tightly orchestrated set of changes/signaling
events in both gene expression and protein activity and is responsible for normal …

Increasing evidence indicates that physical activity and exercise training may delay or
prevent the onset of Alzheimer's disease (AD). However, systemic biomarkers that can …

To determine the relationship between amyloid burden and neural function in healthy adults
at risk for Alzheimer's Disease (AD), we used multimodal imaging with [C-11] Pittsburgh …

Despite interindividual differences in cortical structure, cross‐sectional and longitudinal
studies have demonstrated a large degree of population‐level consistency in age‐related …

Alzheimer's disease (AD) is the most common neurodegenerative disease among the
elderly, affecting millions of people worldwide and clinically characterized by a progressive …

Alzheimer's disease (AD) is a progressive and fatal neurodegenerative disease, with no
effective treatment or cure. A gold standard therapy would be treatment to slow or halt …

Background Structural MRI measures for monitoring Alzheimer's Disease (AD) progression
are becoming instrumental in the clinical practice, and more so in the context of longitudinal …

Cerebral blood flow (CBF) provides an indication of the metabolic status of the cortex and
may have utility in elucidating preclinical brain changes in persons at risk for Alzheimer's …

The last decade has witnessed a proliferation of neuroimaging studies characterising brain
changes associated with Alzheimer's disease (AD), where both widespread atrophy and …