Gastric cancer treatment: recent progress and future perspectives

WL Guan, Y He, RH Xu - Journal of hematology & oncology, 2023 - Springer
Gastric cancer (GC) is one of the most common malignancies worldwide. Most patients are
diagnosed at advanced stages due to the subtle symptoms of earlier disease and the low …

Tumour evolution in hepatocellular carcinoma

AJ Craig, J Von Felden, T Garcia-Lezana… - Nature reviews …, 2020 - nature.com
Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, typically
develops on the background of chronic liver disease and is an aggressive disease with …

Trastuzumab deruxtecan in previously treated HER2-positive gastric cancer

K Shitara, YJ Bang, S Iwasa, N Sugimoto… - … England Journal of …, 2020 - Mass Medical Soc
Abstract Background Trastuzumab deruxtecan (DS-8201) is an antibody-drug conjugate
consisting of an anti-HER2 (human epidermal growth factor receptor 2) antibody, a …

The Chinese Society of Clinical Oncology (CSCO): clinical guidelines for the diagnosis and treatment of gastric cancer, 2021

FH Wang, XT Zhang, YF Li, L Tang, XJ Qu… - Cancer …, 2021 - Wiley Online Library
There exist differences in the epidemiological characteristics, clinicopathological features,
tumor biological characteristics, treatment patterns, and drug selections between gastric …

Mapping the genomic diaspora of gastric cancer

KG Yeoh, P Tan - Nature reviews cancer, 2022 - nature.com
Gastric cancer (GC) is a leading contributor to global cancer incidence and mortality.
Pioneering genomic studies, focusing largely on primary GCs, revealed driver alterations in …

Biomarker-targeted therapies for advanced-stage gastric and gastro-oesophageal junction cancers: an emerging paradigm

Y Nakamura, A Kawazoe, F Lordick… - Nature reviews Clinical …, 2021 - nature.com
Advances in cancer biology and sequencing technology have enabled the selection of
targeted and more effective treatments for individual patients with various types of solid …

Once-daily savolitinib in Chinese patients with pulmonary sarcomatoid carcinomas and other non-small-cell lung cancers harbouring MET exon 14 skipping …

S Lu, J Fang, X Li, L Cao, J Zhou, Q Guo… - The Lancet …, 2021 - thelancet.com
Background Savolitinib is a selective MET tyrosine-kinase inhibitor. We investigated the
activity and safety of savolitinib in patients with pulmonary sarcomatoid carcinoma and other …

Circulating tumor DNA in advanced solid tumors: clinical relevance and future directions

ML Cheng, E Pectasides, GJ Hanna… - CA: a cancer journal …, 2021 - Wiley Online Library
The application of genomic profiling assays using plasma circulating tumor DNA (ctDNA) is
rapidly evolving in the management of patients with advanced solid tumors. Diverse plasma …

Liquid biopsy in gastric cancer: predictive and prognostic biomarkers

Z Zhang, H Wu, W Chong, L Shang, C Jing, L Li - Cell death & disease, 2022 - nature.com
Gastric cancer (GC) is a high-incidence cancer worldwide. Most patients are diagnosed at
an advanced stage, by which time they have limited treatment options and poor prognosis …

Gastric cancer

EC Smyth, M Nilsson, HI Grabsch, NCT van Grieken… - The Lancet, 2020 - thelancet.com
Gastric cancer is the fifth most common cancer and the third most common cause of cancer
death globally. Risk factors for the condition include Helicobacter pylori infection, age, high …