Neutrophils are essential for killing bacteria and other microorganisms, and they also have a
significant role in regulating the inflammatory response. Stimulated neutrophils activate their …

Neutrophils are the most abundant, short lived, and terminally differentiated leukocytes with
distinct tiers of arsenals to counter pathogens. Neutrophils were traditionally considered …

Pseudomonas aeruginosa is a key pathogen of chronic infections in the lungs of cystic
fibrosis patients and in patients suffering from chronic wounds of diverse etiology. In these …

Cystic fibrosis transmembrane conductance regulator (CFTR) functions as a channel that
regulates the transport of ions and the movement of water across the epithelial barrier …

Neutrophil extracellular traps (NETs) are extrusions of intracellular DNA and attached
granular material that enable bacterial killing. NETs are increasingly recognized for their role …

Objectives: Hyperchloremia is frequently observed in critically ill patients in the ICU. Our
study aimed to examine the association of serum chloride (Cl) levels with hospital mortality …

The host inflammatory response in cystic fibrosis (CF) lung disease has long been
recognized as a central pathological feature and an important therapeutic target. Indeed …

Background Cystic fibrosis (CF) lung disease is defined by large numbers of neutrophils and
associated damaging products in the airway. Delayed neutrophil apoptosis is described in …

Human neutrophils represent the predominant leucocyte in circulation and the first
responder to infection. Concurrent with ingestion of microorganisms, neutrophils activate …

Chronic lung disease determines the morbidity and mortality of cystic fibrosis (CF) patients.
The pulmonary immune response in CF is characterized by an early and non-resolving …